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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSF2
All Species:
9.09
Human Site:
S470
Identified Species:
20
UniProt:
Q03933
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03933
NP_001129036.1
536
60348
S470
E
Q
A
S
T
T
A
S
S
E
V
L
S
S
V
Chimpanzee
Pan troglodytes
XP_001155636
135
14602
V70
S
L
T
S
E
D
P
V
T
M
M
D
S
I
L
Rhesus Macaque
Macaca mulatta
XP_001108944
517
58258
A452
Y
T
A
F
P
L
L
A
F
L
D
G
N
P
A
Dog
Lupus familis
XP_533482
578
64802
S513
E
Q
G
S
T
A
S
S
E
V
M
S
S
V
D
Cat
Felis silvestris
Mouse
Mus musculus
P38533
535
60206
S469
E
Q
G
S
T
T
A
S
S
E
V
V
P
S
V
Rat
Rattus norvegicus
NP_113882
513
57725
S448
Q
G
T
T
T
A
S
S
E
V
V
P
S
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P38530
564
62809
A498
T
V
E
S
G
S
S
A
T
E
T
P
S
S
V
Frog
Xenopus laevis
P41154
451
49454
L386
L
D
M
A
V
A
E
L
N
D
H
V
D
N
I
Zebra Danio
Brachydanio rerio
NP_571942
489
55522
T424
M
A
F
L
D
G
C
T
P
L
T
P
S
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22813
691
76915
A543
Q
A
S
T
S
K
A
A
A
K
A
Q
A
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96320
284
31309
C219
E
S
D
E
E
S
E
C
E
G
C
D
G
G
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
96.2
87
N.A.
94.5
91.2
N.A.
N.A.
76.4
35.8
52.6
N.A.
25.4
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
96.4
88.9
N.A.
96.4
93.4
N.A.
N.A.
84.5
53.5
67.3
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
40
N.A.
80
26.6
N.A.
N.A.
33.3
0
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
20
53.3
N.A.
86.6
46.6
N.A.
N.A.
60
40
13.3
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
19
10
0
28
28
28
10
0
10
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% C
% Asp:
0
10
10
0
10
10
0
0
0
10
10
19
10
10
19
% D
% Glu:
37
0
10
10
19
0
19
0
28
28
0
0
0
0
10
% E
% Phe:
0
0
10
10
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
10
19
0
10
10
0
0
0
10
0
10
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% I
% Lys:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% K
% Leu:
10
10
0
10
0
10
10
10
0
19
0
10
0
0
10
% L
% Met:
10
0
10
0
0
0
0
0
0
10
19
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% N
% Pro:
0
0
0
0
10
0
10
0
10
0
0
28
10
10
10
% P
% Gln:
19
28
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
10
46
10
19
28
37
19
0
0
10
55
37
0
% S
% Thr:
10
10
19
19
37
19
0
10
19
0
19
0
0
0
0
% T
% Val:
0
10
0
0
10
0
0
10
0
19
28
19
0
19
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _