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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSF2
All Species:
12.42
Human Site:
S489
Identified Species:
27.33
UniProt:
Q03933
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03933
NP_001129036.1
536
60348
S489
E
V
D
E
L
L
D
S
S
L
D
P
E
P
T
Chimpanzee
Pan troglodytes
XP_001155636
135
14602
L89
N
L
L
G
K
V
E
L
L
D
Y
L
D
S
T
Rhesus Macaque
Macaca mulatta
XP_001108944
517
58258
S471
Q
A
S
T
T
A
S
S
E
V
L
S
S
V
D
Dog
Lupus familis
XP_533482
578
64802
S532
V
D
E
L
L
D
S
S
L
D
P
E
P
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
P38533
535
60206
S488
E
V
D
E
L
L
D
S
S
L
D
P
E
P
T
Rat
Rattus norvegicus
NP_113882
513
57725
N467
V
D
E
L
L
D
S
N
L
D
Q
E
P
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P38530
564
62809
S517
E
V
D
E
L
L
E
S
S
L
D
P
E
P
T
Frog
Xenopus laevis
P41154
451
49454
N405
D
T
L
Q
N
L
L
N
G
Q
S
F
S
V
D
Zebra Danio
Brachydanio rerio
NP_571942
489
55522
S443
P
P
D
L
L
D
E
S
L
E
M
K
T
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22813
691
76915
A562
A
V
A
K
Y
S
G
A
E
N
G
N
N
R
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96320
284
31309
L238
G
V
G
E
G
L
K
L
F
G
V
W
L
K
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
96.2
87
N.A.
94.5
91.2
N.A.
N.A.
76.4
35.8
52.6
N.A.
25.4
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
96.4
88.9
N.A.
96.4
93.4
N.A.
N.A.
84.5
53.5
67.3
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
13.3
N.A.
100
6.6
N.A.
N.A.
93.3
6.6
26.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
20
20
N.A.
100
20
N.A.
N.A.
100
26.6
33.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
10
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
37
0
0
28
19
0
0
28
28
0
10
0
28
% D
% Glu:
28
0
19
37
0
0
28
0
19
10
0
19
28
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% F
% Gly:
10
0
10
10
10
0
10
0
10
10
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
10
0
0
0
0
10
0
10
0
% K
% Leu:
0
10
19
28
55
46
10
19
37
28
10
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
0
19
0
10
0
10
10
0
0
% N
% Pro:
10
10
0
0
0
0
0
0
0
0
10
28
19
37
0
% P
% Gln:
10
0
0
10
0
0
0
0
0
10
10
0
0
0
19
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% R
% Ser:
0
0
10
0
0
10
28
55
28
0
10
10
19
10
0
% S
% Thr:
0
10
0
10
10
0
0
0
0
0
0
0
10
19
37
% T
% Val:
19
46
0
0
0
10
0
0
0
10
10
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _