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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSF2
All Species:
10
Human Site:
T252
Identified Species:
22
UniProt:
Q03933
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03933
NP_001129036.1
536
60348
T252
D
I
I
I
Y
D
V
T
D
D
N
A
D
E
E
Chimpanzee
Pan troglodytes
XP_001155636
135
14602
Rhesus Macaque
Macaca mulatta
XP_001108944
517
58258
L236
P
H
S
R
T
E
G
L
K
P
R
E
R
I
S
Dog
Lupus familis
XP_533482
578
64802
T295
D
I
I
I
Y
D
V
T
D
D
N
A
D
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P38533
535
60206
T252
D
I
I
I
Y
D
V
T
D
D
N
V
D
E
E
Rat
Rattus norvegicus
NP_113882
513
57725
R232
H
H
K
V
P
H
S
R
T
E
G
L
K
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P38530
564
62809
E272
T
E
D
V
A
D
E
E
N
T
M
V
D
E
E
Frog
Xenopus laevis
P41154
451
49454
A170
E
A
L
W
R
E
V
A
S
L
R
Q
K
H
T
Zebra Danio
Brachydanio rerio
NP_571942
489
55522
K208
A
L
N
I
N
G
K
K
S
K
F
I
H
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22813
691
76915
S308
P
A
V
E
R
P
R
S
N
M
S
I
S
S
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96320
284
31309
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
96.2
87
N.A.
94.5
91.2
N.A.
N.A.
76.4
35.8
52.6
N.A.
25.4
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
96.4
88.9
N.A.
96.4
93.4
N.A.
N.A.
84.5
53.5
67.3
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
100
N.A.
93.3
0
N.A.
N.A.
26.6
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
6.6
100
N.A.
93.3
13.3
N.A.
N.A.
40
26.6
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
0
10
0
0
10
0
0
0
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
28
0
10
0
0
37
0
0
28
28
0
0
37
0
0
% D
% Glu:
10
10
0
10
0
19
10
10
0
10
0
10
0
37
37
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
0
% G
% His:
10
19
0
0
0
10
0
0
0
0
0
0
10
10
10
% H
% Ile:
0
28
28
37
0
0
0
0
0
0
0
19
0
10
0
% I
% Lys:
0
0
10
0
0
0
10
10
10
10
0
0
19
0
0
% K
% Leu:
0
10
10
0
0
0
0
10
0
10
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
19
0
28
0
0
0
0
% N
% Pro:
19
0
0
0
10
10
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
10
19
0
10
10
0
0
19
0
10
0
10
% R
% Ser:
0
0
10
0
0
0
10
10
19
0
10
0
10
19
10
% S
% Thr:
10
0
0
0
10
0
0
28
10
10
0
0
0
0
10
% T
% Val:
0
0
10
19
0
0
37
0
0
0
0
19
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
28
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _