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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSF2
All Species:
12.12
Human Site:
T467
Identified Species:
26.67
UniProt:
Q03933
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03933
NP_001129036.1
536
60348
T467
S
S
V
E
Q
A
S
T
T
A
S
S
E
V
L
Chimpanzee
Pan troglodytes
XP_001155636
135
14602
E67
G
S
F
S
L
T
S
E
D
P
V
T
M
M
D
Rhesus Macaque
Macaca mulatta
XP_001108944
517
58258
P449
L
I
Q
Y
T
A
F
P
L
L
A
F
L
D
G
Dog
Lupus familis
XP_533482
578
64802
T510
S
T
V
E
Q
G
S
T
A
S
S
E
V
M
S
Cat
Felis silvestris
Mouse
Mus musculus
P38533
535
60206
T466
S
A
I
E
Q
G
S
T
T
A
S
S
E
V
V
Rat
Rattus norvegicus
NP_113882
513
57725
T445
A
V
E
Q
G
T
T
T
A
S
S
E
V
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P38530
564
62809
G495
P
G
S
T
V
E
S
G
S
S
A
T
E
T
P
Frog
Xenopus laevis
P41154
451
49454
V383
P
P
G
L
D
M
A
V
A
E
L
N
D
H
V
Zebra Danio
Brachydanio rerio
NP_571942
489
55522
D421
C
P
L
M
A
F
L
D
G
C
T
P
L
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22813
691
76915
S540
D
A
N
Q
A
S
T
S
K
A
A
A
K
A
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96320
284
31309
E216
K
P
V
E
S
D
E
E
S
E
C
E
G
C
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
96.2
87
N.A.
94.5
91.2
N.A.
N.A.
76.4
35.8
52.6
N.A.
25.4
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
96.4
88.9
N.A.
96.4
93.4
N.A.
N.A.
84.5
53.5
67.3
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
46.6
N.A.
73.3
20
N.A.
N.A.
13.3
0
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
13.3
66.6
N.A.
93.3
46.6
N.A.
N.A.
40
26.6
13.3
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
0
19
19
10
0
28
28
28
10
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
10
10
0
0
10
0
% C
% Asp:
10
0
0
0
10
10
0
10
10
0
0
0
10
10
19
% D
% Glu:
0
0
10
37
0
10
10
19
0
19
0
28
28
0
0
% E
% Phe:
0
0
10
0
0
10
10
0
0
0
0
10
0
0
0
% F
% Gly:
10
10
10
0
10
19
0
10
10
0
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% K
% Leu:
10
0
10
10
10
0
10
0
10
10
10
0
19
0
10
% L
% Met:
0
0
0
10
0
10
0
0
0
0
0
0
10
19
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
19
28
0
0
0
0
0
10
0
10
0
10
0
0
28
% P
% Gln:
0
0
10
19
28
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
28
19
10
10
10
10
46
10
19
28
37
19
0
0
10
% S
% Thr:
0
10
0
10
10
19
19
37
19
0
10
19
0
19
0
% T
% Val:
0
10
28
0
10
0
0
10
0
0
10
0
19
28
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _