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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GBE1 All Species: 26.06
Human Site: Y469 Identified Species: 57.33
UniProt: Q04446 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q04446 NP_000149.3 702 80460 Y469 Y T L T N R R Y L E K C I A Y
Chimpanzee Pan troglodytes XP_516593 818 92449 Y585 Y T L T N R R Y L E K C I A Y
Rhesus Macaque Macaca mulatta XP_001118968 813 92711 Y580 Y T L T N R R Y L E K C I A Y
Dog Lupus familis XP_535555 705 81278 Y466 Y T L T N R R Y L E K C I A Y
Cat Felis silvestris
Mouse Mus musculus Q9D6Y9 702 80345 Y469 Y T L T N R R Y L E K C V A Y
Rat Rattus norvegicus NP_001093972 702 80400 H469 Y T L T N R R H L E K C V A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425536 693 80105 C455 Y T L T N R R C D E K Y I A Y
Frog Xenopus laevis NP_001086521 688 79334 Y456 H T L I N R R Y N E K C I A Y
Zebra Danio Brachydanio rerio XP_002663606 931 108178 A534 Y Q V T N F F A A S S R F G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q08047 799 90499 W558 H T L T N R R W L E K C V T Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32775 704 81097 Y474 Y T L T N R R Y G E K V V A Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.5 83.7 91.6 N.A. 91.3 91.1 N.A. N.A. 75.6 75.5 48.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 85.6 85.2 95.1 N.A. 95.4 95.7 N.A. N.A. 86.8 87 58.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 86.6 N.A. N.A. 80 80 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 80 86.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 49.6 N.A. N.A. 58.5 N.A.
Protein Similarity: N.A. 64.2 N.A. N.A. 71.1 N.A.
P-Site Identity: N.A. 73.3 N.A. N.A. 80 N.A.
P-Site Similarity: N.A. 93.3 N.A. N.A. 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 10 0 0 0 0 82 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 73 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 91 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 10 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % G
% His: 19 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 55 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 91 0 0 0 0 % K
% Leu: 0 0 91 0 0 0 0 0 64 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 100 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 91 91 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % S
% Thr: 0 91 0 91 0 0 0 0 0 0 0 0 0 10 10 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 10 37 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 82 0 0 0 0 0 0 64 0 0 0 10 0 0 91 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _