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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7A
All Species:
23.03
Human Site:
S427
Identified Species:
46.06
UniProt:
Q04656
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04656
NP_000043.3
1500
163374
S427
E
Y
D
P
L
L
T
S
P
E
T
L
R
G
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
S367
L
P
D
I
W
A
K
S
P
Q
S
T
R
A
V
Dog
Lupus familis
XP_549096
1499
164030
S427
E
Y
D
P
L
L
T
S
P
E
T
L
R
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q64430
1491
161891
S427
E
F
D
P
L
L
T
S
P
E
T
L
R
E
A
Rat
Rattus norvegicus
P70705
1492
162074
S427
E
Y
D
P
L
L
T
S
P
E
P
L
R
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
S536
E
F
D
P
V
L
T
S
P
E
T
L
R
E
V
Chicken
Gallus gallus
XP_420307
1494
162045
C424
E
Y
D
P
L
Q
T
C
P
E
D
L
R
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
S409
E
Y
D
P
L
L
T
S
P
E
E
L
R
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
L288
N
G
E
A
E
V
E
L
E
I
M
G
M
T
C
Honey Bee
Apis mellifera
XP_395837
1274
139224
S308
V
D
I
A
S
S
I
S
E
L
G
F
P
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
T28
P
L
V
R
K
H
L
T
R
S
R
D
G
G
G
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
V38
T
K
C
D
I
S
L
V
T
N
E
C
Q
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
51
92.4
N.A.
89.1
88.7
N.A.
75.1
73.1
N.A.
65.4
N.A.
41.4
44.1
N.A.
N.A.
Protein Similarity:
100
N.A.
67.2
96
N.A.
94.4
94
N.A.
83.5
83.9
N.A.
77.8
N.A.
56.3
58.5
N.A.
N.A.
P-Site Identity:
100
N.A.
26.6
93.3
N.A.
86.6
86.6
N.A.
73.3
66.6
N.A.
86.6
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
40
93.3
N.A.
93.3
86.6
N.A.
86.6
73.3
N.A.
86.6
N.A.
13.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
9
0
0
0
0
0
0
0
17
42
% A
% Cys:
0
0
9
0
0
0
0
9
0
0
0
9
0
0
9
% C
% Asp:
0
9
67
9
0
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
59
0
9
0
9
0
9
0
17
59
17
0
0
34
0
% E
% Phe:
0
17
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
9
9
9
17
9
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
9
0
9
0
0
9
0
0
0
0
0
% I
% Lys:
0
9
0
0
9
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
0
0
50
50
17
9
0
9
0
59
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
9
9
0
59
0
0
0
0
67
0
9
0
9
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
9
0
0
9
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
9
0
9
0
67
0
0
% R
% Ser:
0
0
0
0
9
17
0
67
0
9
9
0
0
9
9
% S
% Thr:
9
0
0
0
0
0
59
9
9
0
34
9
0
17
17
% T
% Val:
9
0
9
0
9
9
0
9
0
0
0
0
0
9
17
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _