KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7A
All Species:
27.88
Human Site:
S833
Identified Species:
55.76
UniProt:
Q04656
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04656
NP_000043.3
1500
163374
S833
D
S
D
N
I
L
L
S
E
E
Q
V
D
V
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
I753
I
T
D
G
S
V
L
I
K
A
T
H
V
G
N
Dog
Lupus familis
XP_549096
1499
164030
S832
D
S
D
N
I
L
L
S
E
E
Q
V
D
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q64430
1491
161891
S824
N
S
E
N
L
L
L
S
E
E
Q
V
D
V
E
Rat
Rattus norvegicus
P70705
1492
162074
S825
N
S
E
N
L
L
L
S
E
E
Q
V
D
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
S943
D
S
E
N
V
L
L
S
E
E
Q
V
D
V
E
Chicken
Gallus gallus
XP_420307
1494
162045
S828
G
P
D
N
I
L
L
S
E
E
Q
V
D
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
S818
N
E
D
M
S
V
L
S
E
E
Q
V
D
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
M674
P
N
L
V
P
V
A
M
E
H
K
M
H
M
D
Honey Bee
Apis mellifera
XP_395837
1274
139224
V694
F
I
P
L
V
I
A
V
S
I
V
T
L
I
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
S414
E
T
S
A
M
L
I
S
F
I
I
L
G
K
Y
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
K424
D
V
E
R
N
E
T
K
E
I
P
I
E
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
51
92.4
N.A.
89.1
88.7
N.A.
75.1
73.1
N.A.
65.4
N.A.
41.4
44.1
N.A.
N.A.
Protein Similarity:
100
N.A.
67.2
96
N.A.
94.4
94
N.A.
83.5
83.9
N.A.
77.8
N.A.
56.3
58.5
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
100
N.A.
80
80
N.A.
86.6
86.6
N.A.
66.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
33.3
100
N.A.
100
100
N.A.
100
86.6
N.A.
80
N.A.
46.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
17
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
42
0
0
0
0
0
0
0
0
0
59
0
9
% D
% Glu:
9
9
34
0
0
9
0
0
75
59
0
0
9
0
59
% E
% Phe:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
0
0
0
0
0
0
0
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% H
% Ile:
9
9
0
0
25
9
9
9
0
25
9
9
0
9
9
% I
% Lys:
0
0
0
0
0
0
0
9
9
0
9
0
0
9
0
% K
% Leu:
0
0
9
9
17
59
67
0
0
0
0
9
9
9
9
% L
% Met:
0
0
0
9
9
0
0
9
0
0
0
9
0
9
0
% M
% Asn:
25
9
0
50
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
9
9
9
0
9
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
59
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
42
9
0
17
0
0
67
9
0
0
0
0
0
0
% S
% Thr:
0
17
0
0
0
0
9
0
0
0
9
9
0
0
0
% T
% Val:
0
9
0
9
17
25
0
9
0
0
9
59
9
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _