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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7A
All Species:
13.64
Human Site:
Y532
Identified Species:
27.27
UniProt:
Q04656
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04656
NP_000043.3
1500
163374
Y532
A
G
K
A
E
V
R
Y
N
P
A
V
I
Q
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
I471
C
A
S
C
V
H
N
I
E
S
K
L
T
R
T
Dog
Lupus familis
XP_549096
1499
164030
Y531
A
G
K
A
E
V
R
Y
N
P
V
V
I
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q64430
1491
161891
V532
P
A
V
I
Q
P
R
V
I
A
E
F
I
R
E
Rat
Rattus norvegicus
P70705
1492
162074
P531
Y
N
P
A
V
I
Q
P
R
V
I
A
E
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
Y641
A
G
K
A
E
V
R
Y
N
P
A
V
V
Q
P
Chicken
Gallus gallus
XP_420307
1494
162045
H533
R
Y
N
P
A
V
I
H
P
S
A
I
A
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
Y517
A
S
K
A
E
V
R
Y
S
P
S
V
I
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
Y392
P
C
M
V
A
M
I
Y
F
M
L
E
M
S
D
Honey Bee
Apis mellifera
XP_395837
1274
139224
K412
D
Q
K
E
E
I
N
K
W
R
T
A
F
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
R132
E
R
S
R
Q
V
C
R
I
R
I
N
G
M
T
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
G142
R
E
M
I
E
D
C
G
F
D
S
N
I
I
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
51
92.4
N.A.
89.1
88.7
N.A.
75.1
73.1
N.A.
65.4
N.A.
41.4
44.1
N.A.
N.A.
Protein Similarity:
100
N.A.
67.2
96
N.A.
94.4
94
N.A.
83.5
83.9
N.A.
77.8
N.A.
56.3
58.5
N.A.
N.A.
P-Site Identity:
100
N.A.
0
93.3
N.A.
13.3
6.6
N.A.
93.3
13.3
N.A.
73.3
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
93.3
N.A.
26.6
20
N.A.
100
33.3
N.A.
86.6
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
17
0
42
17
0
0
0
0
9
25
17
9
0
0
% A
% Cys:
9
9
0
9
0
0
17
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
9
0
0
0
9
9
% D
% Glu:
9
9
0
9
50
0
0
0
9
0
9
9
9
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
17
0
0
9
9
0
0
% F
% Gly:
0
25
0
0
0
0
0
9
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
17
17
9
17
0
17
9
42
9
9
% I
% Lys:
0
0
42
0
0
0
0
9
0
0
9
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
9
9
0
17
9
% L
% Met:
0
0
17
0
0
9
0
0
0
9
0
0
9
9
9
% M
% Asn:
0
9
9
0
0
0
17
0
25
0
0
17
0
0
0
% N
% Pro:
17
0
9
9
0
9
0
9
9
34
0
0
0
0
34
% P
% Gln:
0
9
0
0
17
0
9
0
0
0
0
0
0
25
0
% Q
% Arg:
17
9
0
9
0
0
42
9
9
17
0
0
0
17
0
% R
% Ser:
0
9
17
0
0
0
0
0
9
17
17
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
17
% T
% Val:
0
0
9
9
17
50
0
9
0
9
9
34
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
0
0
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _