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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OCA2 All Species: 10.3
Human Site: S110 Identified Species: 25.19
UniProt: Q04671 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q04671 NP_000266.2 838 92850 S110 N S L Q E K G S R C I P V Y H
Chimpanzee Pan troglodytes XP_001162129 838 92687 S110 N S L Q E K G S R C I P V Y H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545800 827 92861 Y101 W E L L D N A Y I R F R L L K
Cat Felis silvestris
Mouse Mus musculus Q62052 833 91850 S106 N S S Q K K R S Q L M P V H H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506110 498 55429
Chicken Gallus gallus XP_425579 726 81522 V76 L V L F I F V V V C S I L F G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_695807 757 85046 T100 L G M T R L I T I F V I V V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_723024 812 90884 A101 G I N V T N E A G Q V R V L D
Honey Bee Apis mellifera XP_624260 1119 126463 I385 S S I I L G Q I P E E V L R V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780555 697 78024 D47 M D T A I D N D D N N D T C N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 N.A. 77.9 N.A. 76.9 N.A. N.A. 41.8 64 N.A. 62.1 N.A. 38.4 31.9 N.A. 40.8
Protein Similarity: 100 98.9 N.A. 84.2 N.A. 84.7 N.A. N.A. 48.8 75.3 N.A. 73.8 N.A. 57.2 48.3 N.A. 57.5
P-Site Identity: 100 100 N.A. 6.6 N.A. 53.3 N.A. N.A. 0 13.3 N.A. 6.6 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 100 N.A. 20 N.A. 80 N.A. N.A. 0 26.6 N.A. 26.6 N.A. 20 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 10 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 30 0 0 0 10 0 % C
% Asp: 0 10 0 0 10 10 0 10 10 0 0 10 0 0 10 % D
% Glu: 0 10 0 0 20 0 10 0 0 10 10 0 0 0 0 % E
% Phe: 0 0 0 10 0 10 0 0 0 10 10 0 0 10 0 % F
% Gly: 10 10 0 0 0 10 20 0 10 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 30 % H
% Ile: 0 10 10 10 20 0 10 10 20 0 20 20 0 0 0 % I
% Lys: 0 0 0 0 10 30 0 0 0 0 0 0 0 0 10 % K
% Leu: 20 0 40 10 10 10 0 0 0 10 0 0 30 20 10 % L
% Met: 10 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 30 0 10 0 0 20 10 0 0 10 10 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 30 0 0 0 % P
% Gln: 0 0 0 30 0 0 10 0 10 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 10 0 20 10 0 20 0 10 0 % R
% Ser: 10 40 10 0 0 0 0 30 0 0 10 0 0 0 0 % S
% Thr: 0 0 10 10 10 0 0 10 0 0 0 0 10 0 0 % T
% Val: 0 10 0 10 0 0 10 10 10 0 20 10 50 10 10 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 20 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _