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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OCA2 All Species: 5.45
Human Site: S141 Identified Species: 13.33
UniProt: Q04671 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q04671 NP_000266.2 838 92850 S141 W E R R Y L L S R E V S G L S
Chimpanzee Pan troglodytes XP_001162129 838 92687 S141 W E R R Y L L S R E V S G L S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545800 827 92861 F132 V V V C S I L F S L Y P D Q G
Cat Felis silvestris
Mouse Mus musculus Q62052 833 91850 G137 W E Q K C M L G K E V A D L S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506110 498 55429
Chicken Gallus gallus XP_425579 726 81522 L107 L Q S F S M N L T D F H D S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_695807 757 85046 E131 M L A V S S T E S F S M N L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_723024 812 90884 R132 P H A K S L I R K Y L I W F K
Honey Bee Apis mellifera XP_624260 1119 126463 V416 F Q R E Y D R V H H T V G G R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780555 697 78024 T78 F V C T V F F T L K D E V N P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 N.A. 77.9 N.A. 76.9 N.A. N.A. 41.8 64 N.A. 62.1 N.A. 38.4 31.9 N.A. 40.8
Protein Similarity: 100 98.9 N.A. 84.2 N.A. 84.7 N.A. N.A. 48.8 75.3 N.A. 73.8 N.A. 57.2 48.3 N.A. 57.5
P-Site Identity: 100 100 N.A. 6.6 N.A. 46.6 N.A. N.A. 0 0 N.A. 6.6 N.A. 6.6 20 N.A. 0
P-Site Similarity: 100 100 N.A. 13.3 N.A. 80 N.A. N.A. 0 26.6 N.A. 13.3 N.A. 33.3 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 0 0 0 0 0 0 0 10 0 0 10 % A
% Cys: 0 0 10 10 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 10 10 0 30 0 0 % D
% Glu: 0 30 0 10 0 0 0 10 0 30 0 10 0 0 0 % E
% Phe: 20 0 0 10 0 10 10 10 0 10 10 0 0 10 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 0 30 10 10 % G
% His: 0 10 0 0 0 0 0 0 10 10 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 10 10 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 20 0 0 0 0 20 10 0 0 0 0 10 % K
% Leu: 10 10 0 0 0 30 40 10 10 10 10 0 0 40 0 % L
% Met: 10 0 0 0 0 20 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 10 10 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % P
% Gln: 0 20 10 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 30 20 0 0 10 10 20 0 0 0 0 0 10 % R
% Ser: 0 0 10 0 40 10 0 20 20 0 10 20 0 10 30 % S
% Thr: 0 0 0 10 0 0 10 10 10 0 10 0 0 0 10 % T
% Val: 10 20 10 10 10 0 0 10 0 0 30 10 10 0 0 % V
% Trp: 30 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 30 0 0 0 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _