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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EMX2
All Species:
10
Human Site:
S25
Identified Species:
22
UniProt:
Q04743
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04743
NP_004089.1
252
28303
S25
K
D
S
P
L
P
A
S
R
S
E
D
P
I
R
Chimpanzee
Pan troglodytes
XP_001149718
165
18129
Rhesus Macaque
Macaca mulatta
XP_001103417
257
28020
A40
S
H
L
L
A
A
A
A
S
E
E
P
L
R
P
Dog
Lupus familis
XP_540233
251
26337
A23
A
R
G
G
G
S
S
A
E
P
G
G
G
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q04744
253
28382
S25
K
D
S
P
L
P
A
S
R
S
E
D
P
I
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514550
249
28171
S25
K
D
S
P
L
P
A
S
R
S
E
D
P
I
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q91770
233
26710
P18
G
H
H
L
A
D
Y
P
A
M
P
L
A
T
D
Zebra Danio
Brachydanio rerio
Q804S6
231
26490
V16
C
F
T
I
E
S
L
V
A
K
E
S
P
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18488
497
53766
R166
G
L
S
P
L
Q
T
R
L
S
P
E
T
E
Q
Honey Bee
Apis mellifera
XP_624481
523
56130
A138
E
G
S
S
S
P
R
A
R
R
V
A
T
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26656
405
44721
S89
P
T
D
K
H
R
K
S
P
R
S
P
P
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.8
65.7
44
N.A.
99.2
N.A.
N.A.
96
N.A.
27.3
65
N.A.
27.1
27.9
N.A.
23.9
Protein Similarity:
100
53.9
76.2
52.7
N.A.
99.2
N.A.
N.A.
97.6
N.A.
41.2
75
N.A.
34.6
35.9
N.A.
35.3
P-Site Identity:
100
0
13.3
0
N.A.
100
N.A.
N.A.
100
N.A.
0
20
N.A.
26.6
20
N.A.
13.3
P-Site Similarity:
100
0
20
13.3
N.A.
100
N.A.
N.A.
100
N.A.
0
26.6
N.A.
40
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
19
10
37
28
19
0
0
10
10
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
28
10
0
0
10
0
0
0
0
0
28
0
0
10
% D
% Glu:
10
0
0
0
10
0
0
0
10
10
46
10
0
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
10
10
10
0
0
0
0
0
10
10
10
0
10
% G
% His:
0
19
10
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
37
0
% I
% Lys:
28
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% K
% Leu:
0
10
10
19
37
0
10
0
10
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
37
0
37
0
10
10
10
19
19
46
0
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
10
10
10
37
19
0
0
0
28
28
% R
% Ser:
10
0
46
10
10
19
10
37
10
37
10
10
0
0
19
% S
% Thr:
0
10
10
0
0
0
10
0
0
0
0
0
19
10
10
% T
% Val:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _