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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGFAC
All Species:
5.45
Human Site:
S376
Identified Species:
13.33
UniProt:
Q04756
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04756
NP_001519.1
655
70682
S376
S
L
T
R
V
Q
L
S
P
D
L
L
A
T
L
Chimpanzee
Pan troglodytes
XP_001174601
567
61413
A299
L
A
T
L
P
E
P
A
S
P
G
R
Q
A
C
Rhesus Macaque
Macaca mulatta
P12545
810
90237
E527
T
N
P
R
A
G
L
E
K
N
Y
C
R
N
P
Dog
Lupus familis
XP_861645
657
70405
T378
L
A
R
I
P
S
L
T
T
A
V
L
L
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9R098
653
70549
T374
L
A
R
V
H
S
Q
T
P
E
I
L
A
A
L
Rat
Rattus norvegicus
Q6L711
558
62075
M291
G
S
L
Q
E
P
V
M
E
L
P
G
F
D
S
Wallaby
Macropus eugenll
O18783
806
90963
T406
T
P
H
Q
H
K
K
T
P
D
N
F
P
N
A
Platypus
Ornith. anatinus
XP_001513341
549
61470
D282
T
L
S
P
P
V
V
D
V
F
N
T
C
G
K
Chicken
Gallus gallus
P15120
434
49381
F167
R
T
C
G
Q
R
S
F
S
K
Y
F
K
I
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103843
497
55990
P230
S
E
T
E
P
E
K
P
L
T
T
P
T
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
23.2
84.4
N.A.
80.6
31.9
22.9
30.3
27.6
N.A.
30
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
85.6
35.3
88.7
N.A.
86.5
45.3
35.9
43.6
40.4
N.A.
44.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
13.3
N.A.
26.6
0
13.3
6.6
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
26.6
33.3
N.A.
46.6
13.3
40
26.6
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
0
10
0
0
10
0
10
0
0
20
20
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
10
% C
% Asp:
0
0
0
0
0
0
0
10
0
20
0
0
0
10
0
% D
% Glu:
0
10
0
10
10
20
0
10
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
10
0
20
10
0
0
% F
% Gly:
10
0
0
10
0
10
0
0
0
0
10
10
0
10
0
% G
% His:
0
0
10
0
20
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
0
0
0
0
0
10
20
0
10
10
0
0
10
10
10
% K
% Leu:
30
20
10
10
0
0
30
0
10
10
10
30
10
0
30
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
20
0
0
20
0
% N
% Pro:
0
10
10
10
40
10
10
10
30
10
10
10
10
0
10
% P
% Gln:
0
0
0
20
10
10
10
0
0
0
0
0
10
0
10
% Q
% Arg:
10
0
20
20
0
10
0
0
0
0
0
10
10
0
0
% R
% Ser:
20
10
10
0
0
20
10
10
20
0
0
0
0
10
10
% S
% Thr:
30
10
30
0
0
0
0
30
10
10
10
10
10
10
0
% T
% Val:
0
0
0
10
10
10
20
0
10
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _