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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
20.61
Human Site:
S323
Identified Species:
30.22
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
S323
V
E
I
G
L
P
C
S
I
K
N
E
A
R
P
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
S323
V
E
I
G
L
P
C
S
I
K
N
E
A
R
P
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
S768
R
A
S
R
R
S
D
S
A
S
S
E
P
V
G
Dog
Lupus familis
XP_849292
706
81555
S323
V
E
I
G
L
P
C
S
I
K
G
E
A
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
S323
V
E
I
G
L
P
C
S
T
K
N
E
T
R
P
Rat
Rattus norvegicus
Q9WTQ0
707
81732
S323
I
E
I
S
F
P
R
S
I
K
S
E
T
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
K325
I
G
L
T
N
P
T
K
P
G
T
T
L
L
P
Chicken
Gallus gallus
NP_001006133
699
80179
Q312
V
E
N
V
G
I
Y
Q
D
F
D
K
K
P
R
Frog
Xenopus laevis
Q7LZQ8
671
76506
P288
E
Y
F
N
V
P
V
P
P
E
G
E
E
G
N
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
E292
F
N
V
P
V
P
P
E
G
E
E
G
N
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
T282
S
C
M
S
L
A
V
T
G
S
G
G
V
G
A
Honey Bee
Apis mellifera
XP_394743
624
71014
H278
R
N
S
D
S
S
D
H
F
P
S
G
R
I
T
Nematode Worm
Caenorhab. elegans
P34722
704
80280
S325
L
H
L
N
G
E
T
S
K
N
N
G
S
L
P
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
A278
S
F
G
K
V
M
L
A
E
Q
K
G
T
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
L695
D
D
L
M
R
D
E
L
E
L
W
K
A
Q
R
Red Bread Mold
Neurospora crassa
P87253
1142
127954
S691
S
Q
P
S
Q
A
G
S
I
P
D
F
G
G
S
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
13.3
86.6
N.A.
86.6
60
N.A.
13.3
13.3
13.3
6.6
N.A.
6.6
0
20
0
P-Site Similarity:
100
100
20
86.6
N.A.
86.6
73.3
N.A.
26.6
26.6
26.6
26.6
N.A.
20
6.6
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
13
0
7
7
0
0
0
25
0
7
% A
% Cys:
0
7
0
0
0
0
25
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
7
0
7
13
0
7
0
13
0
0
0
0
% D
% Glu:
7
38
0
0
0
7
7
7
13
13
7
44
7
7
7
% E
% Phe:
7
7
7
0
7
0
0
0
7
7
0
7
0
0
0
% F
% Gly:
0
7
7
25
13
0
7
0
13
7
19
32
7
19
7
% G
% His:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
13
0
32
0
0
7
0
0
32
0
0
0
0
7
0
% I
% Lys:
0
0
0
7
0
0
0
7
7
32
7
13
7
7
7
% K
% Leu:
7
0
19
0
32
0
7
7
0
7
0
0
7
13
7
% L
% Met:
0
0
7
7
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
7
13
7
0
0
0
0
7
25
0
7
0
7
% N
% Pro:
0
0
7
7
0
50
7
7
13
13
0
0
7
7
38
% P
% Gln:
0
7
0
0
7
0
0
7
0
7
0
0
0
7
0
% Q
% Arg:
13
0
0
7
13
0
7
0
0
0
0
0
7
32
13
% R
% Ser:
19
0
13
19
7
13
0
50
0
13
19
0
7
0
7
% S
% Thr:
0
0
0
7
0
0
13
7
7
0
7
7
19
0
7
% T
% Val:
32
0
7
7
19
0
13
0
0
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _