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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
36.67
Human Site:
T219
Identified Species:
53.78
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
T219
S
A
I
N
S
R
E
T
M
F
H
K
E
R
F
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
T219
S
A
I
N
S
R
E
T
M
F
H
K
E
R
F
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
T682
T
A
A
N
S
R
D
T
I
F
Q
K
E
R
F
Dog
Lupus familis
XP_849292
706
81555
T219
S
A
I
N
S
R
E
T
M
F
H
K
E
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
T219
S
A
I
N
S
R
E
T
M
F
H
K
E
R
F
Rat
Rattus norvegicus
Q9WTQ0
707
81732
T219
S
A
I
N
S
R
E
T
M
F
H
K
E
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
T219
S
A
V
N
S
R
E
T
M
F
H
K
E
R
F
Chicken
Gallus gallus
NP_001006133
699
80179
T216
T
A
A
N
S
R
D
T
M
F
Q
K
E
R
F
Frog
Xenopus laevis
Q7LZQ8
671
76506
L195
L
S
D
P
Y
V
K
L
K
L
I
P
D
P
K
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
K204
L
K
L
I
P
D
P
K
S
E
S
K
Q
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
N199
V
A
N
T
C
G
I
N
T
K
Q
M
A
E
I
Honey Bee
Apis mellifera
XP_394743
624
71014
C193
T
F
M
S
P
T
F
C
D
H
C
G
S
M
L
Nematode Worm
Caenorhab. elegans
P34722
704
80280
T225
S
A
K
N
T
K
E
T
M
A
L
K
E
R
F
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
G193
N
N
V
P
N
L
C
G
V
N
Q
R
L
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
F447
F
Q
C
Q
D
C
K
F
L
C
H
K
K
C
Y
Red Bread Mold
Neurospora crassa
P87253
1142
127954
T513
I
S
K
S
N
A
E
T
D
P
D
E
E
K
I
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
66.6
100
N.A.
100
100
N.A.
93.3
73.3
0
6.6
N.A.
6.6
0
66.6
0
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
100
86.6
20
26.6
N.A.
6.6
20
80
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
63
13
0
0
7
0
0
0
7
0
0
7
0
0
% A
% Cys:
0
0
7
0
7
7
7
7
0
7
7
0
0
7
0
% C
% Asp:
0
0
7
0
7
7
13
0
13
0
7
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
50
0
0
7
0
7
63
7
0
% E
% Phe:
7
7
0
0
0
0
7
7
0
50
0
0
0
0
57
% F
% Gly:
0
0
0
0
0
7
0
7
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
44
0
0
0
0
% H
% Ile:
7
0
32
7
0
0
7
0
7
0
7
0
0
0
13
% I
% Lys:
0
7
13
0
0
7
13
7
7
7
0
69
7
13
7
% K
% Leu:
13
0
7
0
0
7
0
7
7
7
7
0
7
7
7
% L
% Met:
0
0
7
0
0
0
0
0
50
0
0
7
0
7
0
% M
% Asn:
7
7
7
57
13
0
0
7
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
13
13
0
7
0
0
7
0
7
0
7
0
% P
% Gln:
0
7
0
7
0
0
0
0
0
0
25
0
7
0
0
% Q
% Arg:
0
0
0
0
0
50
0
0
0
0
0
7
0
57
0
% R
% Ser:
44
13
0
13
50
0
0
0
7
0
7
0
7
0
7
% S
% Thr:
19
0
0
7
7
7
0
63
7
0
0
0
0
0
7
% T
% Val:
7
0
13
0
0
7
0
0
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _