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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
15.45
Human Site:
T335
Identified Species:
22.67
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
T335
A
R
P
P
C
L
P
T
P
G
K
R
E
P
Q
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
T335
A
R
P
P
C
L
P
T
L
G
K
R
E
P
Q
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
F780
P
V
G
I
Y
Q
G
F
E
K
K
T
G
V
A
Dog
Lupus familis
XP_849292
706
81555
A335
A
R
L
P
C
V
P
A
P
G
K
K
E
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
T335
T
R
P
P
C
V
P
T
P
G
K
R
E
P
Q
Rat
Rattus norvegicus
Q9WTQ0
707
81732
T335
T
R
P
P
C
V
P
T
P
G
K
S
E
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
T337
L
L
P
L
P
I
P
T
A
G
R
K
E
P
Q
Chicken
Gallus gallus
NP_001006133
699
80179
D324
K
P
R
G
P
G
G
D
T
G
D
N
S
Q
Y
Frog
Xenopus laevis
Q7LZQ8
671
76506
Q300
E
G
N
E
E
L
R
Q
K
F
E
R
A
K
I
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
F304
N
E
E
L
R
Q
K
F
E
R
A
K
I
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
R294
V
G
A
T
G
E
T
R
P
G
K
C
S
L
L
Honey Bee
Apis mellifera
XP_394743
624
71014
N290
R
I
T
P
P
A
T
N
L
P
R
F
K
K
Y
Nematode Worm
Caenorhab. elegans
P34722
704
80280
N337
S
L
P
N
K
L
K
N
L
F
K
S
H
Q
Y
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
K290
T
K
K
Y
F
A
I
K
A
L
K
K
E
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
L707
A
Q
R
E
E
M
E
L
E
I
K
Q
D
S
G
Red Bread Mold
Neurospora crassa
P87253
1142
127954
R703
G
G
S
P
G
Y
G
R
P
D
S
R
D
D
E
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
93.3
6.6
73.3
N.A.
86.6
80
N.A.
46.6
6.6
13.3
0
N.A.
20
6.6
20
13.3
P-Site Similarity:
100
93.3
6.6
86.6
N.A.
93.3
86.6
N.A.
66.6
6.6
20
6.6
N.A.
20
20
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
7
0
0
13
0
7
13
0
7
0
7
0
7
% A
% Cys:
0
0
0
0
32
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
7
7
0
13
7
0
% D
% Glu:
7
7
7
13
13
7
7
0
19
0
7
0
44
0
7
% E
% Phe:
0
0
0
0
7
0
0
13
0
13
0
7
0
0
0
% F
% Gly:
7
19
7
7
13
7
19
0
0
50
0
0
7
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
0
7
0
7
7
0
0
7
0
0
7
0
7
% I
% Lys:
7
7
7
0
7
0
13
7
7
7
63
25
7
13
0
% K
% Leu:
7
13
7
13
0
25
0
7
19
7
0
0
0
7
7
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
7
0
0
0
13
0
0
0
7
0
0
0
% N
% Pro:
7
7
38
44
19
0
38
0
38
7
0
0
0
38
7
% P
% Gln:
0
7
0
0
0
13
0
7
0
0
0
7
0
13
38
% Q
% Arg:
7
32
13
0
7
0
7
13
0
7
13
32
0
0
0
% R
% Ser:
7
0
7
0
0
0
0
0
0
0
7
13
13
7
0
% S
% Thr:
19
0
7
7
0
0
13
32
7
0
0
7
0
0
0
% T
% Val:
7
7
0
0
0
19
0
0
0
0
0
0
0
13
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
7
0
0
0
0
0
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _