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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACVR1
All Species:
50.3
Human Site:
S244
Identified Species:
92.22
UniProt:
Q04771
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04771
NP_001096.1
509
57153
S244
F
S
S
R
D
E
K
S
W
F
R
E
T
E
L
Chimpanzee
Pan troglodytes
XP_001145163
509
57107
S244
F
S
S
R
D
E
K
S
W
F
R
E
T
E
L
Rhesus Macaque
Macaca mulatta
XP_001088916
509
57116
S244
F
S
S
R
D
E
K
S
W
F
R
E
T
E
L
Dog
Lupus familis
XP_549615
509
57276
S244
F
S
S
R
D
E
K
S
W
F
R
E
T
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P37172
509
57207
S244
F
S
S
R
D
E
K
S
W
F
R
E
T
E
L
Rat
Rattus norvegicus
P80201
509
57176
S244
F
S
S
R
D
E
K
S
W
F
R
E
T
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509625
512
57592
S247
F
S
S
R
D
E
K
S
W
F
R
E
T
E
L
Chicken
Gallus gallus
Q90ZK6
504
56206
S239
F
S
S
R
D
E
K
S
W
F
R
E
T
E
L
Frog
Xenopus laevis
P27041
511
57917
S225
F
P
V
Q
D
K
Q
S
W
Q
C
E
K
E
I
Zebra Danio
Brachydanio rerio
NP_571420
506
56709
S241
F
S
S
R
D
E
K
S
W
F
R
E
T
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523652
570
64210
S300
F
F
S
R
D
E
E
S
W
K
R
E
T
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09488
636
72217
S301
F
Y
T
T
D
E
D
S
W
K
N
E
R
D
V
Sea Urchin
Strong. purpuratus
XP_794984
512
58526
S240
F
S
S
I
D
E
K
S
W
F
R
E
T
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
99.2
N.A.
98.4
97.2
N.A.
87.5
83.5
33.6
66.2
N.A.
50.1
N.A.
30.9
54.6
Protein Similarity:
100
100
100
99.6
N.A.
99.4
99
N.A.
94.1
90.9
52.8
77.2
N.A.
62.8
N.A.
46.5
67.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
40
93.3
N.A.
73.3
N.A.
40
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
66.6
100
N.A.
86.6
N.A.
60
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
100
0
8
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
93
8
0
0
0
0
100
0
93
0
% E
% Phe:
100
8
0
0
0
0
0
0
0
77
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
31
% I
% Lys:
0
0
0
0
0
8
77
0
0
16
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
77
0
0
0
0
0
0
85
0
8
0
0
% R
% Ser:
0
77
85
0
0
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
0
0
85
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _