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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKR1C1
All Species:
17.27
Human Site:
Y81
Identified Species:
76
UniProt:
Q04828
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04828
NP_001344.2
323
36788
Y81
V
K
R
E
D
I
F
Y
T
S
K
L
W
C
N
Chimpanzee
Pan troglodytes
XP_001143472
368
42059
Y81
V
K
R
E
D
I
F
Y
T
S
K
L
W
C
N
Rhesus Macaque
Macaca mulatta
XP_001103545
323
36944
Y81
V
K
R
E
D
I
F
Y
T
S
K
L
W
C
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70694
323
37029
Y81
V
K
R
E
D
I
F
Y
T
S
K
V
W
C
T
Rat
Rattus norvegicus
P51652
323
37281
Y81
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6AZW2
324
36744
L80
D
I
F
V
T
S
K
L
W
N
T
K
H
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.6
94.1
N.A.
N.A.
76.7
68.7
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
84.7
98.7
N.A.
N.A.
90
85.4
N.A.
N.A.
N.A.
N.A.
66.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
86.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% C
% Asp:
17
0
0
0
84
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
84
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
17
0
0
0
84
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
17
17
0
% H
% Ile:
0
17
0
0
0
84
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
84
0
0
0
0
17
0
0
0
84
17
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
17
0
0
0
67
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
84
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
17
0
0
0
84
0
0
0
17
0
% S
% Thr:
0
0
0
0
17
0
0
0
84
0
17
0
0
0
34
% T
% Val:
84
0
0
17
0
0
0
0
0
0
0
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
17
0
0
0
84
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _