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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNE
All Species:
26.67
Human Site:
S339
Identified Species:
65.19
UniProt:
Q04844
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04844
NP_000071.1
493
54697
S339
T
P
T
T
H
A
M
S
P
R
L
R
H
V
L
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
P338
T
P
T
T
H
T
M
P
R
W
V
K
T
V
F
Rhesus Macaque
Macaca mulatta
XP_001097094
493
54680
S339
T
P
T
T
H
S
M
S
P
R
L
R
H
V
L
Dog
Lupus familis
XP_536608
492
54288
S339
T
P
T
T
H
A
M
S
P
R
L
R
H
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P20782
493
54896
S339
T
P
T
T
H
A
T
S
P
R
L
R
Q
I
L
Rat
Rattus norvegicus
P09660
494
54930
S339
T
P
T
T
H
A
T
S
P
R
L
R
Q
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02713
514
58907
S341
T
P
N
T
H
S
M
S
Q
R
V
R
Q
V
W
Frog
Xenopus laevis
P49580
504
57770
S340
S
P
S
T
H
N
L
S
T
K
V
K
H
M
L
Zebra Danio
Brachydanio rerio
NP_996947
518
60339
T343
T
P
S
T
H
V
M
T
E
W
T
K
E
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09478
567
64001
A338
S
P
V
T
H
R
M
A
P
W
V
Q
R
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.8
95.9
87
N.A.
88.6
87.6
N.A.
N.A.
52.9
52.5
43.4
N.A.
32
N.A.
N.A.
N.A.
Protein Similarity:
100
54.2
97.3
92.6
N.A.
93
92.1
N.A.
N.A.
68.2
71
61.7
N.A.
50.6
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
93.3
100
N.A.
80
80
N.A.
N.A.
60
40
33.3
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
100
N.A.
86.6
86.6
N.A.
N.A.
73.3
86.6
53.3
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
40
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
30
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
100
0
0
0
0
0
0
0
40
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
30
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
50
0
0
10
60
% L
% Met:
0
0
0
0
0
0
70
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
100
0
0
0
0
0
10
60
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
10
30
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
10
60
0
60
10
0
0
% R
% Ser:
20
0
20
0
0
20
0
70
0
0
0
0
0
0
0
% S
% Thr:
80
0
60
100
0
10
20
10
10
0
10
0
10
0
0
% T
% Val:
0
0
10
0
0
10
0
0
0
0
40
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _