KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REL
All Species:
10.3
Human Site:
S403
Identified Species:
22.67
UniProt:
Q04864
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04864
NP_002899.1
619
68520
S403
S
G
L
S
H
H
A
S
M
A
P
L
P
S
S
Chimpanzee
Pan troglodytes
XP_001159537
619
68348
S403
S
G
L
S
H
H
A
S
M
A
P
L
P
S
S
Rhesus Macaque
Macaca mulatta
XP_001115312
619
68464
S403
S
G
L
S
H
H
A
S
M
T
P
L
P
S
S
Dog
Lupus familis
XP_531836
593
65808
S376
H
H
S
S
P
I
P
S
M
V
S
Q
A
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P15307
587
64942
H371
I
S
S
G
L
P
H
H
P
P
A
I
P
S
V
Rat
Rattus norvegicus
NP_954888
550
60249
R336
R
R
I
A
V
P
S
R
G
P
T
S
V
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512346
573
64146
H356
N
P
N
T
I
S
H
H
A
S
N
I
R
P
L
Chicken
Gallus gallus
P16236
598
66829
F384
P
S
C
W
Q
Q
L
F
S
S
S
P
S
A
S
Frog
Xenopus laevis
Q04865
527
59040
N315
N
F
K
H
Y
V
K
N
N
P
F
A
G
G
E
Zebra Danio
Brachydanio rerio
NP_001001841
596
67208
L370
P
V
Y
Y
N
K
G
L
R
S
C
P
M
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15330
999
111533
P612
A
G
L
Q
G
R
A
P
L
Q
V
E
D
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
81.7
N.A.
71.2
38.6
N.A.
59.6
49.4
41.8
44.5
N.A.
25.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.3
86.4
N.A.
79.6
54.9
N.A.
69.3
64.3
56.2
58.3
N.A.
38.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
33.3
N.A.
13.3
0
N.A.
0
6.6
0
0
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
33.3
N.A.
20
20
N.A.
26.6
20
20
13.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
37
0
10
19
10
10
10
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% E
% Phe:
0
10
0
0
0
0
0
10
0
0
10
0
0
0
10
% F
% Gly:
0
37
0
10
10
0
10
0
10
0
0
0
10
10
0
% G
% His:
10
10
0
10
28
28
19
19
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
10
10
0
0
0
0
0
19
0
0
0
% I
% Lys:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
37
0
10
0
10
10
10
0
0
28
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
37
0
0
0
10
10
0
% M
% Asn:
19
0
10
0
10
0
0
10
10
0
10
0
0
0
0
% N
% Pro:
19
10
0
0
10
19
10
10
10
28
28
19
37
19
10
% P
% Gln:
0
0
0
10
10
10
0
0
0
10
0
10
0
0
0
% Q
% Arg:
10
10
0
0
0
10
0
10
10
0
0
0
10
0
0
% R
% Ser:
28
19
19
37
0
10
10
37
10
28
19
10
10
55
46
% S
% Thr:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% T
% Val:
0
10
0
0
10
10
0
0
0
10
10
0
10
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _