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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSTF1 All Species: 26.06
Human Site: S206 Identified Species: 47.78
UniProt: Q05048 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05048 NP_001028693.1 431 48358 S206 L F D Y S K P S A K R A F K Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094819 354 39333 A130 I A T G S A D A S I K I L D T
Dog Lupus familis XP_867349 428 48209 S203 T L K L F D Y S K P S A K R A
Cat Felis silvestris
Mouse Mus musculus Q9D7H2 328 36014 K103 L V S A S D D K T L K V W D M
Rat Rattus norvegicus Q5BJQ6 431 48363 S206 L F D Y S K P S A K R A F K Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509506 431 48390 S206 L F D Y S K P S A K R A F K Y
Chicken Gallus gallus XP_417500 537 59846 S312 L F D Y S K P S A K R A F K Y
Frog Xenopus laevis NP_001087924 431 48448 S206 L F D Y S K P S A K R A F K H
Zebra Danio Brachydanio rerio NP_997835 367 40490 K143 D T E R M L A K S A M P L E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023 K136 L V S G S D D K T L K V W E L
Honey Bee Apis mellifera XP_393185 436 48252 S211 L F D F S K A S V K K A F R T
Nematode Worm Caenorhab. elegans Q17963 376 40375 K151 V V S A S D D K T L K I F E I
Sea Urchin Strong. purpuratus XP_001188174 410 45121 T186 L F D F S K S T V K K S A K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 81.4 98.1 N.A. 22.2 99.5 N.A. 98.6 78.7 93.9 66.5 N.A. 22 58.2 22.5 58.9
Protein Similarity: 100 N.A. 81.9 98.3 N.A. 37.3 99.7 N.A. 99.5 79.8 97.6 73.7 N.A. 42 72.9 42 71.9
P-Site Identity: 100 N.A. 6.6 13.3 N.A. 13.3 100 N.A. 100 100 93.3 0 N.A. 13.3 60 13.3 46.6
P-Site Similarity: 100 N.A. 33.3 20 N.A. 26.6 100 N.A. 100 100 100 20 N.A. 33.3 80 33.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 16 0 8 16 8 39 8 0 54 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 54 0 0 31 31 0 0 0 0 0 0 16 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 0 0 24 0 % E
% Phe: 0 54 0 16 8 0 0 0 0 0 0 0 54 0 0 % F
% Gly: 0 0 0 16 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 0 0 0 0 0 0 8 0 16 0 0 8 % I
% Lys: 0 0 8 0 0 54 0 31 8 54 47 0 8 47 0 % K
% Leu: 70 8 0 8 0 8 0 0 0 24 0 0 16 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 39 0 0 8 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 39 0 0 16 0 % R
% Ser: 0 0 24 0 85 0 8 54 16 0 8 8 0 0 8 % S
% Thr: 8 8 8 0 0 0 0 8 24 0 0 0 0 0 16 % T
% Val: 8 24 0 0 0 0 0 0 16 0 0 16 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % W
% Tyr: 0 0 0 39 0 0 8 0 0 0 0 0 0 0 31 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _