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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSTF1
All Species:
18.79
Human Site:
T298
Identified Species:
34.44
UniProt:
Q05048
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05048
NP_001028693.1
431
48358
T298
G
V
S
N
R
C
I
T
T
F
E
K
A
H
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094819
354
39333
S222
Q
E
A
E
M
L
R
S
I
S
F
H
P
S
G
Dog
Lupus familis
XP_867349
428
48209
R295
L
W
D
G
V
S
N
R
C
I
T
T
F
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7H2
328
36014
A195
L
C
R
I
W
D
A
A
S
G
Q
C
L
R
T
Rat
Rattus norvegicus
Q5BJQ6
431
48363
T298
G
V
S
N
R
C
I
T
T
F
E
K
A
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509506
431
48390
T298
G
V
S
N
R
C
I
T
T
F
E
K
A
H
D
Chicken
Gallus gallus
XP_417500
537
59846
T404
G
V
S
N
R
C
I
T
T
F
E
K
A
H
D
Frog
Xenopus laevis
NP_001087924
431
48448
T298
G
V
S
N
R
C
V
T
T
Y
E
K
A
H
D
Zebra Danio
Brachydanio rerio
NP_997835
367
40490
G235
S
G
D
F
L
L
V
G
T
Q
H
P
T
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
A228
L
C
R
I
W
D
T
A
S
G
Q
C
L
K
T
Honey Bee
Apis mellifera
XP_393185
436
48252
N303
G
V
S
N
R
C
I
N
T
F
V
K
A
H
D
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
A243
L
V
R
I
W
D
T
A
N
G
Q
C
I
K
T
Sea Urchin
Strong. purpuratus
XP_001188174
410
45121
N278
G
V
S
N
R
C
I
N
T
L
K
D
A
H
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
81.4
98.1
N.A.
22.2
99.5
N.A.
98.6
78.7
93.9
66.5
N.A.
22
58.2
22.5
58.9
Protein Similarity:
100
N.A.
81.9
98.3
N.A.
37.3
99.7
N.A.
99.5
79.8
97.6
73.7
N.A.
42
72.9
42
71.9
P-Site Identity:
100
N.A.
0
0
N.A.
0
100
N.A.
100
100
86.6
6.6
N.A.
0
86.6
6.6
66.6
P-Site Similarity:
100
N.A.
13.3
0
N.A.
13.3
100
N.A.
100
100
100
13.3
N.A.
13.3
86.6
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
24
0
0
0
0
54
0
0
% A
% Cys:
0
16
0
0
0
54
0
0
8
0
0
24
0
0
0
% C
% Asp:
0
0
16
0
0
24
0
0
0
0
0
8
0
0
47
% D
% Glu:
0
8
0
8
0
0
0
0
0
0
39
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
39
8
0
8
0
0
% F
% Gly:
54
8
0
8
0
0
0
8
0
24
0
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
0
54
0
% H
% Ile:
0
0
0
24
0
0
47
0
8
8
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
47
0
16
8
% K
% Leu:
31
0
0
0
8
16
0
0
0
8
0
0
16
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
54
0
0
8
16
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
24
0
0
0
0
% Q
% Arg:
0
0
24
0
54
0
8
8
0
0
0
0
0
8
8
% R
% Ser:
8
0
54
0
0
8
0
8
16
8
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
16
39
62
0
8
8
8
0
24
% T
% Val:
0
62
0
0
8
0
16
0
0
0
8
0
0
0
0
% V
% Trp:
0
8
0
0
24
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _