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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSTF1
All Species:
21.82
Human Site:
Y277
Identified Species:
40
UniProt:
Q05048
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05048
NP_001028693.1
431
48358
Y277
Y
N
S
S
A
N
M
Y
V
T
G
S
K
D
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094819
354
39333
D201
D
Y
T
L
K
L
F
D
Y
S
K
P
S
A
K
Dog
Lupus familis
XP_867349
428
48209
A274
S
V
N
Y
N
P
S
A
N
M
Y
V
T
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7H2
328
36014
N174
P
I
S
A
V
N
F
N
C
N
G
S
L
I
V
Rat
Rattus norvegicus
Q5BJQ6
431
48363
Y277
Y
N
P
S
A
N
M
Y
V
T
G
S
K
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509506
431
48390
Y277
Y
N
P
S
A
N
M
Y
V
T
G
S
K
D
G
Chicken
Gallus gallus
XP_417500
537
59846
Y383
Y
N
A
S
A
N
M
Y
V
T
G
S
K
D
G
Frog
Xenopus laevis
NP_001087924
431
48448
Y277
Y
N
P
T
A
N
T
Y
V
T
C
S
K
D
G
Zebra Danio
Brachydanio rerio
NP_997835
367
40490
V214
A
K
R
A
F
K
H
V
Q
E
A
E
M
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3J8
361
39023
N207
P
V
S
A
V
H
F
N
R
D
G
S
L
I
V
Honey Bee
Apis mellifera
XP_393185
436
48252
Y282
Y
S
P
D
A
K
T
Y
A
S
A
G
K
D
G
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
N222
P
V
S
A
V
S
F
N
R
D
G
S
L
I
A
Sea Urchin
Strong. purpuratus
XP_001188174
410
45121
Y257
Y
S
P
L
G
N
M
Y
A
S
C
S
N
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
81.4
98.1
N.A.
22.2
99.5
N.A.
98.6
78.7
93.9
66.5
N.A.
22
58.2
22.5
58.9
Protein Similarity:
100
N.A.
81.9
98.3
N.A.
37.3
99.7
N.A.
99.5
79.8
97.6
73.7
N.A.
42
72.9
42
71.9
P-Site Identity:
100
N.A.
0
0
N.A.
26.6
93.3
N.A.
93.3
93.3
73.3
0
N.A.
20
40
20
46.6
P-Site Similarity:
100
N.A.
13.3
6.6
N.A.
33.3
93.3
N.A.
93.3
100
80
6.6
N.A.
33.3
53.3
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
31
47
0
0
8
16
0
16
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
16
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
8
0
16
0
0
0
54
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
31
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
54
8
0
8
54
% G
% His:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
24
0
% I
% Lys:
0
8
0
0
8
16
0
0
0
0
8
0
47
0
8
% K
% Leu:
0
0
0
16
0
8
0
0
0
0
0
0
24
8
0
% L
% Met:
0
0
0
0
0
0
39
0
0
8
0
0
8
0
0
% M
% Asn:
0
39
8
0
8
54
0
24
8
8
0
0
8
0
0
% N
% Pro:
24
0
39
0
0
8
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
16
0
0
0
0
0
8
% R
% Ser:
8
16
31
31
0
8
8
0
0
24
0
70
8
0
8
% S
% Thr:
0
0
8
8
0
0
16
0
0
39
0
0
8
0
0
% T
% Val:
0
24
0
0
24
0
0
8
39
0
0
8
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
54
8
0
8
0
0
0
54
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _