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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1
All Species:
9.39
Human Site:
S333
Identified Species:
17.22
UniProt:
Q05084
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05084
NP_001129492.1
483
54645
S333
L
S
A
L
D
K
G
S
T
H
T
A
C
S
G
Chimpanzee
Pan troglodytes
XP_518971
483
54670
S333
L
S
A
L
D
K
S
S
T
H
T
A
C
S
G
Rhesus Macaque
Macaca mulatta
XP_001086048
484
54745
A333
L
S
A
L
D
K
S
A
T
H
T
A
G
S
G
Dog
Lupus familis
XP_850551
483
54711
S333
L
S
A
L
D
K
S
S
T
H
N
A
C
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P97411
478
54364
G328
V
L
S
S
V
D
K
G
S
V
H
D
T
C
S
Rat
Rattus norvegicus
Q63054
480
54644
S330
V
P
S
S
V
D
K
S
S
A
D
D
A
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
F321
S
L
F
Q
M
S
E
F
G
A
S
Q
L
S
G
Chicken
Gallus gallus
XP_418682
516
58625
C332
L
S
K
L
Q
G
N
C
N
H
K
Q
N
S
G
Frog
Xenopus laevis
NP_001080094
512
57900
L330
S
G
F
E
E
I
L
L
E
N
S
V
G
A
L
Zebra Danio
Brachydanio rerio
NP_001002730
449
50173
N304
E
Q
E
T
Q
S
S
N
T
T
H
T
G
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
L338
D
K
Q
D
E
K
L
L
D
I
E
Y
E
T
K
Nematode Worm
Caenorhab. elegans
P91124
430
48887
E285
T
G
T
K
P
E
R
E
R
K
S
E
K
E
E
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
E463
I
S
L
G
E
D
P
E
R
H
I
D
Q
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.9
94.1
N.A.
88.8
89.4
N.A.
49.2
70.3
66.2
57.3
N.A.
N.A.
39.2
35.2
37.3
Protein Similarity:
100
99.5
98.1
97
N.A.
92.9
94
N.A.
62.7
76.1
74.2
68.3
N.A.
N.A.
54.5
50
47.6
P-Site Identity:
100
93.3
80
86.6
N.A.
0
6.6
N.A.
13.3
40
0
6.6
N.A.
N.A.
6.6
0
20
P-Site Similarity:
100
93.3
86.6
86.6
N.A.
20
26.6
N.A.
20
40
26.6
20
N.A.
N.A.
20
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
0
0
0
0
8
0
16
0
31
8
16
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
24
16
0
% C
% Asp:
8
0
0
8
31
24
0
0
8
0
8
24
0
0
8
% D
% Glu:
8
0
8
8
24
8
8
16
8
0
8
8
8
8
8
% E
% Phe:
0
0
16
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
16
0
8
0
8
8
8
8
0
0
0
24
8
54
% G
% His:
0
0
0
0
0
0
0
0
0
47
16
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
8
8
8
0
39
16
0
0
8
8
0
8
0
8
% K
% Leu:
39
16
8
39
0
0
16
16
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
8
8
8
0
8
0
0
% N
% Pro:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
8
16
0
0
0
0
0
0
16
8
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
16
0
0
0
0
0
0
% R
% Ser:
16
47
16
16
0
16
31
31
16
0
24
0
0
47
16
% S
% Thr:
8
0
8
8
0
0
0
0
39
8
24
8
8
8
0
% T
% Val:
16
0
0
0
16
0
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _