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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1
All Species:
27.58
Human Site:
S391
Identified Species:
50.56
UniProt:
Q05084
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05084
NP_001129492.1
483
54645
S391
S
L
E
E
G
E
F
S
K
E
W
A
A
V
F
Chimpanzee
Pan troglodytes
XP_518971
483
54670
S391
S
L
E
E
G
E
F
S
K
E
W
A
A
V
F
Rhesus Macaque
Macaca mulatta
XP_001086048
484
54745
S391
S
L
E
E
G
E
F
S
K
E
W
A
A
V
F
Dog
Lupus familis
XP_850551
483
54711
S391
S
L
D
E
G
E
F
S
K
E
W
A
A
V
F
Cat
Felis silvestris
Mouse
Mus musculus
P97411
478
54364
S386
C
L
D
E
G
E
F
S
R
E
W
A
A
V
F
Rat
Rattus norvegicus
Q63054
480
54644
S388
S
L
D
E
G
E
F
S
R
E
W
A
A
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
P379
G
Q
P
G
S
S
F
P
T
Q
V
A
S
S
E
Chicken
Gallus gallus
XP_418682
516
58625
S390
S
L
E
E
G
E
F
S
K
E
W
T
A
V
F
Frog
Xenopus laevis
NP_001080094
512
57900
G388
S
L
E
G
D
D
L
G
N
E
W
A
A
I
F
Zebra Danio
Brachydanio rerio
NP_001002730
449
50173
E362
A
E
T
Q
T
T
D
E
E
A
D
F
F
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
I396
N
V
S
H
T
D
I
I
Q
E
G
T
Q
S
E
Nematode Worm
Caenorhab. elegans
P91124
430
48887
R343
I
E
D
V
D
D
E
R
R
K
T
G
D
L
L
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
Y521
D
K
D
D
F
G
A
Y
I
S
A
D
L
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.9
94.1
N.A.
88.8
89.4
N.A.
49.2
70.3
66.2
57.3
N.A.
N.A.
39.2
35.2
37.3
Protein Similarity:
100
99.5
98.1
97
N.A.
92.9
94
N.A.
62.7
76.1
74.2
68.3
N.A.
N.A.
54.5
50
47.6
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
13.3
93.3
53.3
0
N.A.
N.A.
6.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
26.6
93.3
66.6
26.6
N.A.
N.A.
33.3
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
8
8
62
62
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
39
8
16
24
8
0
0
0
8
8
8
0
0
% D
% Glu:
0
16
39
54
0
54
8
8
8
70
0
0
0
0
16
% E
% Phe:
0
0
0
0
8
0
62
0
0
0
0
8
8
0
62
% F
% Gly:
8
0
0
16
54
8
0
8
0
0
8
8
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
8
8
0
0
0
0
8
0
% I
% Lys:
0
8
0
0
0
0
0
0
39
8
0
0
0
0
0
% K
% Leu:
0
62
0
0
0
0
8
0
0
0
0
0
8
24
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% P
% Gln:
0
8
0
8
0
0
0
0
8
8
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
24
0
0
0
0
0
0
% R
% Ser:
54
0
8
0
8
8
0
54
0
8
0
0
8
16
8
% S
% Thr:
0
0
8
0
16
8
0
0
8
0
8
16
0
0
0
% T
% Val:
0
8
0
8
0
0
0
0
0
0
8
0
0
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _