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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1
All Species:
37.88
Human Site:
Y259
Identified Species:
69.44
UniProt:
Q05084
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05084
NP_001129492.1
483
54645
Y259
I
H
E
S
F
K
G
Y
Q
P
Y
E
F
T
T
Chimpanzee
Pan troglodytes
XP_518971
483
54670
Y259
I
H
E
S
F
K
G
Y
Q
P
Y
E
F
T
T
Rhesus Macaque
Macaca mulatta
XP_001086048
484
54745
Y259
I
H
E
S
F
K
G
Y
Q
P
Y
E
F
T
T
Dog
Lupus familis
XP_850551
483
54711
Y259
I
H
E
S
F
K
G
Y
Q
P
Y
E
F
T
T
Cat
Felis silvestris
Mouse
Mus musculus
P97411
478
54364
Y258
I
H
E
S
F
K
G
Y
Q
P
Y
E
F
T
T
Rat
Rattus norvegicus
Q63054
480
54644
Y258
I
H
E
S
F
K
G
Y
Q
P
Y
E
F
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
V252
I
H
E
E
F
T
E
V
H
P
Y
D
F
V
V
Chicken
Gallus gallus
XP_418682
516
58625
Y261
I
H
E
S
F
K
G
Y
Q
P
Y
E
F
T
M
Frog
Xenopus laevis
NP_001080094
512
57900
Y261
I
H
E
S
F
K
G
Y
Q
P
Y
E
F
T
T
Zebra Danio
Brachydanio rerio
NP_001002730
449
50173
H237
T
Y
Q
T
T
L
L
H
F
W
E
K
T
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
Y269
I
A
N
S
F
K
G
Y
Q
R
Y
D
F
M
V
Nematode Worm
Caenorhab. elegans
P91124
430
48887
T218
L
D
R
L
K
T
D
T
L
Q
K
V
D
L
L
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
Y367
V
Q
E
G
F
R
G
Y
Q
H
Y
E
F
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.9
94.1
N.A.
88.8
89.4
N.A.
49.2
70.3
66.2
57.3
N.A.
N.A.
39.2
35.2
37.3
Protein Similarity:
100
99.5
98.1
97
N.A.
92.9
94
N.A.
62.7
76.1
74.2
68.3
N.A.
N.A.
54.5
50
47.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
46.6
93.3
100
0
N.A.
N.A.
60
0
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
53.3
93.3
100
40
N.A.
N.A.
66.6
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
0
0
0
16
8
0
0
% D
% Glu:
0
0
77
8
0
0
8
0
0
0
8
70
0
0
0
% E
% Phe:
0
0
0
0
85
0
0
0
8
0
0
0
85
0
0
% F
% Gly:
0
0
0
8
0
0
77
0
0
0
0
0
0
0
0
% G
% His:
0
70
0
0
0
0
0
8
8
8
0
0
0
0
8
% H
% Ile:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
70
0
0
0
0
8
8
0
0
0
% K
% Leu:
8
0
0
8
0
8
8
0
8
0
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
16
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
77
8
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
70
0
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
8
0
0
8
8
16
0
8
0
0
0
0
8
62
54
% T
% Val:
8
0
0
0
0
0
0
8
0
0
0
8
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
77
0
0
85
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _