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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
24.24
Human Site:
T272
Identified Species:
41.03
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
T272
P
N
V
E
C
D
L
T
Y
H
N
V
Y
S
R
Chimpanzee
Pan troglodytes
XP_510256
879
101065
T276
P
N
V
E
C
D
L
T
Y
H
N
V
Y
S
R
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
T276
P
N
V
E
C
D
L
T
Y
H
N
V
Y
S
R
Dog
Lupus familis
XP_848240
875
100388
T272
P
N
V
E
C
D
L
T
Y
H
N
V
Y
S
R
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
T283
P
N
V
E
C
D
L
T
Y
H
N
V
Y
T
R
Rat
Rattus norvegicus
Q5PQN1
1057
118521
T429
I
A
N
E
I
D
G
T
F
S
S
S
G
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
E266
L
E
L
C
R
E
R
E
D
Y
S
P
L
I
R
Chicken
Gallus gallus
XP_416882
880
100974
T277
P
N
V
E
C
D
L
T
Y
H
N
V
Y
S
R
Frog
Xenopus laevis
Q6DCL5
944
106566
V356
N
K
T
P
R
N
Q
V
F
K
V
R
N
V
S
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
F269
D
P
N
Y
L
N
V
F
I
I
V
M
E
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
G329
A
G
G
G
A
A
V
G
P
P
G
V
A
G
P
Honey Bee
Apis mellifera
XP_394656
898
100748
F308
I
E
L
D
L
R
V
F
R
I
M
P
G
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
I278
Q
M
A
D
V
E
V
I
V
N
P
L
F
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
C285
S
Y
E
L
A
K
R
C
I
G
Y
L
S
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
100
N.A.
93.3
20
N.A.
6.6
100
0
0
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
33.3
100
13.3
26.6
N.A.
13.3
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
15
8
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
8
43
0
0
8
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
15
0
50
0
0
8
0
0
0
0
8
8
% D
% Glu:
0
15
8
50
0
15
0
8
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
15
0
0
0
8
0
0
% F
% Gly:
0
8
8
8
0
0
8
8
0
8
8
0
15
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
43
0
0
0
0
0
% H
% Ile:
15
0
0
0
8
0
0
8
15
15
0
0
0
8
0
% I
% Lys:
0
8
0
0
0
8
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
15
8
15
0
43
0
0
0
0
15
8
0
15
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
8
43
15
0
0
15
0
0
0
8
43
0
8
15
8
% N
% Pro:
43
8
0
8
0
0
0
0
8
8
8
15
0
0
8
% P
% Gln:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
15
8
15
0
8
0
0
8
0
0
50
% R
% Ser:
8
0
0
0
0
0
0
0
0
8
15
8
8
36
15
% S
% Thr:
0
0
8
0
0
0
0
50
0
0
0
0
0
8
0
% T
% Val:
0
0
43
0
8
0
29
8
8
0
15
50
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
0
0
43
8
8
0
43
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _