KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
25.15
Human Site:
T408
Identified Species:
42.56
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
T408
I
P
E
S
S
E
L
T
L
Q
E
L
L
G
E
Chimpanzee
Pan troglodytes
XP_510256
879
101065
T412
I
P
E
S
S
E
L
T
L
Q
E
L
L
G
E
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
T412
I
P
E
S
S
E
L
T
L
Q
E
L
L
G
E
Dog
Lupus familis
XP_848240
875
100388
T408
I
P
E
S
S
E
L
T
L
Q
E
L
L
G
E
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
T419
I
P
E
S
S
E
L
T
L
Q
E
L
L
G
D
Rat
Rattus norvegicus
Q5PQN1
1057
118521
E565
K
I
V
E
L
F
K
E
V
V
V
H
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
D402
Y
H
N
V
Y
S
R
D
P
N
Y
L
N
L
F
Chicken
Gallus gallus
XP_416882
880
100974
T413
I
P
E
S
S
E
L
T
L
Q
E
L
L
G
E
Frog
Xenopus laevis
Q6DCL5
944
106566
Q492
N
R
L
S
A
V
I
Q
A
F
Y
M
C
C
S
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
P405
E
R
R
N
K
K
G
P
R
V
D
P
L
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
T465
Q
Q
Q
P
T
A
V
T
A
Q
V
T
Q
D
D
Honey Bee
Apis mellifera
XP_394656
898
100748
S444
D
K
S
G
R
S
L
S
Q
I
P
Q
D
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
D414
E
E
E
L
N
L
Q
D
F
L
G
A
L
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
N421
Y
V
A
N
T
R
R
N
G
R
G
A
L
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
6.6
100
6.6
6.6
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
6.6
100
26.6
26.6
N.A.
40
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
0
0
15
0
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
8
0
0
0
0
0
0
15
0
0
8
0
8
8
15
% D
% Glu:
15
8
50
8
0
43
0
8
0
0
43
0
0
8
36
% E
% Phe:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
8
0
8
0
15
0
0
50
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% H
% Ile:
43
8
0
0
0
0
8
0
0
8
0
0
0
0
8
% I
% Lys:
8
8
0
0
8
8
8
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
8
8
8
8
50
0
43
8
0
50
72
15
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
8
15
8
0
0
8
0
8
0
0
8
0
0
% N
% Pro:
0
43
0
8
0
0
0
8
8
0
8
8
0
8
0
% P
% Gln:
8
8
8
0
0
0
8
8
8
50
0
8
8
0
0
% Q
% Arg:
0
15
8
0
8
8
15
0
8
8
0
0
0
0
0
% R
% Ser:
0
0
8
50
43
15
0
8
0
0
0
0
0
8
8
% S
% Thr:
0
0
0
0
15
0
0
50
0
0
0
8
0
0
8
% T
% Val:
0
8
8
8
0
8
8
0
8
15
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
8
0
0
0
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _