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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
20
Human Site:
Y96
Identified Species:
33.85
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
Y96
K
K
G
A
S
S
A
Y
L
E
N
S
K
G
A
Chimpanzee
Pan troglodytes
XP_510256
879
101065
Y100
K
K
G
A
S
S
A
Y
L
E
N
S
K
G
A
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
Y100
K
K
G
A
S
S
A
Y
L
E
N
S
K
G
A
Dog
Lupus familis
XP_848240
875
100388
Y94
K
K
G
A
S
S
A
Y
L
E
N
S
K
G
A
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
S108
P
S
K
K
G
A
S
S
A
Y
L
E
N
S
K
Rat
Rattus norvegicus
Q5PQN1
1057
118521
L99
G
E
A
H
T
L
A
L
N
D
K
G
Q
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
S96
H
S
D
D
I
E
A
S
R
M
F
T
A
R
R
Chicken
Gallus gallus
XP_416882
880
100974
Y94
K
K
G
T
S
S
A
Y
L
E
N
N
S
K
G
Frog
Xenopus laevis
Q6DCL5
944
106566
D158
V
Q
H
V
T
N
V
D
V
E
D
A
M
G
Q
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
H94
C
S
N
G
K
M
N
H
K
D
L
P
P
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
S107
T
V
L
I
T
P
N
S
T
L
H
F
K
V
L
Honey Bee
Apis mellifera
XP_394656
898
100748
L98
S
K
V
A
R
T
T
L
E
P
G
P
A
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
S105
P
A
A
Q
P
S
T
S
F
A
R
N
T
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
V111
A
C
Q
V
T
V
I
V
K
E
P
E
I
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
100
N.A.
0
6.6
N.A.
6.6
66.6
13.3
0
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
13.3
33.3
N.A.
13.3
73.3
53.3
13.3
N.A.
20
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
36
0
8
50
0
8
8
0
8
15
0
29
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
8
0
15
8
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
0
0
8
50
0
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% F
% Gly:
8
0
36
8
8
0
0
0
0
0
8
8
0
36
8
% G
% His:
8
0
8
8
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
8
0
0
0
0
0
8
0
0
% I
% Lys:
36
43
8
8
8
0
0
0
15
0
8
0
36
8
8
% K
% Leu:
0
0
8
0
0
8
0
15
36
8
15
0
0
0
15
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
8
15
0
8
0
36
15
8
8
0
% N
% Pro:
15
0
0
0
8
8
0
0
0
8
8
15
8
8
0
% P
% Gln:
0
8
8
8
0
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
0
0
0
0
8
0
0
0
8
0
8
0
0
8
15
% R
% Ser:
8
22
0
0
36
43
8
29
0
0
0
29
8
15
15
% S
% Thr:
8
0
0
8
29
8
15
0
8
0
0
8
8
8
0
% T
% Val:
8
8
8
15
0
8
8
8
8
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
36
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _