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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNM1 All Species: 15.45
Human Site: S774 Identified Species: 34
UniProt: Q05193 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05193 NP_001005336.1 864 97408 S774 S V P A G R R S P T S S P T P
Chimpanzee Pan troglodytes XP_520289 967 108830 V852 V D S Y M A I V N K T V R D L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547462 848 95550 S755 A P P P V D D S W I Q H S R R
Cat Felis silvestris
Mouse Mus musculus P39053 867 97784 S774 S V P A G R R S P T S S P T P
Rat Rattus norvegicus P21575 864 97276 S774 S V P A G R R S P T S S P T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233250 865 97255 S774 S V P S G R R S P T S S P T P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SXN5 691 77244 I602 E Q R D C E V I E R L I K S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27619 877 97791 G770 L S P P S P G G V R G K P G P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P39055 830 93389 S737 K E A L R I I S E V N M S T L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LFT2 780 86625 E691 L V N Y T K R E L H N V F I E
Baker's Yeast Sacchar. cerevisiae P54861 757 84953 L668 P L T E R E E L E C E L I K R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.6 N.A. 78.3 N.A. 97.5 98 N.A. N.A. 96.1 N.A. 36 N.A. 65.6 N.A. 63.3 N.A.
Protein Similarity: 100 79.6 N.A. 86.3 N.A. 98.2 99.5 N.A. N.A. 98.8 N.A. 53.5 N.A. 78.1 N.A. 77.7 N.A.
P-Site Identity: 100 0 N.A. 13.3 N.A. 100 100 N.A. N.A. 93.3 N.A. 0 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 6.6 N.A. 20 N.A. 100 100 N.A. N.A. 100 N.A. 6.6 N.A. 20 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 36.2 36.1 N.A.
Protein Similarity: N.A. N.A. N.A. 53.8 53.8 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 28 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 10 0 10 0 10 10 0 0 0 0 0 0 10 0 % D
% Glu: 10 10 0 10 0 19 10 10 28 0 10 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 37 0 10 10 0 0 10 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 10 19 10 0 10 0 10 10 10 0 % I
% Lys: 10 0 0 0 0 10 0 0 0 10 0 10 10 10 0 % K
% Leu: 19 10 0 10 0 0 0 10 10 0 10 10 0 0 19 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 10 0 19 0 0 0 0 % N
% Pro: 10 10 55 19 0 10 0 0 37 0 0 0 46 0 46 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 10 0 19 37 46 0 0 19 0 0 10 10 19 % R
% Ser: 37 10 10 10 10 0 0 55 0 0 37 37 19 10 0 % S
% Thr: 0 0 10 0 10 0 0 0 0 37 10 0 0 46 0 % T
% Val: 10 46 0 0 10 0 10 10 10 10 0 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _