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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM1
All Species:
23.94
Human Site:
T274
Identified Species:
52.67
UniProt:
Q05193
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05193
NP_001005336.1
864
97408
T274
H
L
A
D
R
M
G
T
P
Y
L
Q
K
V
L
Chimpanzee
Pan troglodytes
XP_520289
967
108830
K292
D
R
V
T
G
T
N
K
G
I
S
P
V
P
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547462
848
95550
T274
H
I
A
D
R
M
G
T
P
H
L
Q
K
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P39053
867
97784
T274
H
L
A
D
R
M
G
T
P
Y
L
Q
K
V
L
Rat
Rattus norvegicus
P21575
864
97276
T274
H
L
A
D
R
M
G
T
P
Y
L
Q
K
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233250
865
97255
T274
H
M
A
D
R
M
G
T
P
Y
L
Q
K
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
K132
S
D
E
P
I
H
L
K
I
F
S
P
H
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
T269
H
M
A
D
R
L
G
T
P
Y
L
Q
R
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P39055
830
93389
H264
E
R
K
F
F
I
S
H
P
S
Y
R
H
M
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
T221
A
D
P
D
G
H
R
T
I
G
V
I
T
K
L
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
L198
I
E
K
Q
I
K
N
L
I
L
D
Y
I
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.6
N.A.
78.3
N.A.
97.5
98
N.A.
N.A.
96.1
N.A.
36
N.A.
65.6
N.A.
63.3
N.A.
Protein Similarity:
100
79.6
N.A.
86.3
N.A.
98.2
99.5
N.A.
N.A.
98.8
N.A.
53.5
N.A.
78.1
N.A.
77.7
N.A.
P-Site Identity:
100
0
N.A.
86.6
N.A.
100
100
N.A.
N.A.
93.3
N.A.
6.6
N.A.
80
N.A.
6.6
N.A.
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
N.A.
100
N.A.
20
N.A.
100
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.2
36.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
53.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
55
0
0
0
0
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
0
64
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
19
0
55
0
10
10
0
0
0
0
0
% G
% His:
55
0
0
0
0
19
0
10
0
10
0
0
19
0
0
% H
% Ile:
10
10
0
0
19
10
0
0
28
10
0
10
10
0
10
% I
% Lys:
0
0
19
0
0
10
0
19
0
0
0
0
46
10
0
% K
% Leu:
0
28
0
0
0
10
10
10
0
10
55
0
0
0
64
% L
% Met:
0
19
0
0
0
46
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
0
0
0
0
64
0
0
19
0
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
55
0
0
0
% Q
% Arg:
0
19
0
0
55
0
10
0
0
0
0
10
10
0
0
% R
% Ser:
10
0
0
0
0
0
10
0
0
10
19
0
0
0
0
% S
% Thr:
0
0
0
10
0
10
0
64
0
0
0
0
10
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
10
0
10
64
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
46
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _