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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM1
All Species:
19.09
Human Site:
T443
Identified Species:
42
UniProt:
Q05193
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05193
NP_001005336.1
864
97408
T443
I
S
T
V
R
Q
C
T
K
K
L
Q
Q
Y
P
Chimpanzee
Pan troglodytes
XP_520289
967
108830
K521
Q
F
A
V
D
F
E
K
R
I
E
G
S
G
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547462
848
95550
S424
I
V
K
L
K
G
P
S
L
K
S
V
D
L
V
Cat
Felis silvestris
Mouse
Mus musculus
P39053
867
97784
T443
I
S
T
V
R
Q
C
T
K
K
L
Q
Q
Y
P
Rat
Rattus norvegicus
P21575
864
97276
S443
T
S
T
I
R
K
C
S
E
K
L
Q
Q
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233250
865
97255
T443
I
N
T
V
R
Q
C
T
K
K
L
S
Q
Y
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
K271
E
H
G
F
L
Q
K
K
Y
P
S
L
A
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
T439
S
V
V
V
R
M
C
T
A
K
M
S
R
Y
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P39055
830
93389
F406
H
G
I
R
V
G
L
F
T
P
D
M
A
F
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
Y360
I
T
K
Y
C
E
A
Y
S
S
T
L
E
G
K
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
T337
D
K
L
P
D
I
K
T
K
L
N
T
L
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.6
N.A.
78.3
N.A.
97.5
98
N.A.
N.A.
96.1
N.A.
36
N.A.
65.6
N.A.
63.3
N.A.
Protein Similarity:
100
79.6
N.A.
86.3
N.A.
98.2
99.5
N.A.
N.A.
98.8
N.A.
53.5
N.A.
78.1
N.A.
77.7
N.A.
P-Site Identity:
100
6.6
N.A.
13.3
N.A.
100
66.6
N.A.
N.A.
86.6
N.A.
6.6
N.A.
46.6
N.A.
0
N.A.
P-Site Similarity:
100
13.3
N.A.
33.3
N.A.
100
93.3
N.A.
N.A.
93.3
N.A.
6.6
N.A.
60
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.2
36.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.8
53.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
0
10
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
10
0
46
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
19
0
0
0
0
0
10
0
10
0
10
% D
% Glu:
10
0
0
0
0
10
10
0
10
0
10
0
10
0
10
% E
% Phe:
0
10
0
10
0
10
0
10
0
0
0
0
0
10
0
% F
% Gly:
0
10
10
0
0
19
0
0
0
0
0
10
0
19
0
% G
% His:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
46
0
10
10
0
10
0
0
0
10
0
0
0
10
0
% I
% Lys:
0
10
19
0
10
10
19
19
37
55
0
0
0
0
10
% K
% Leu:
0
0
10
10
10
0
10
0
10
10
37
19
10
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
10
10
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
0
0
10
0
% N
% Pro:
0
0
0
10
0
0
10
0
0
19
0
0
0
0
46
% P
% Gln:
10
0
0
0
0
37
0
0
0
0
0
28
37
0
0
% Q
% Arg:
0
0
0
10
46
0
0
0
10
0
0
0
10
0
10
% R
% Ser:
10
28
0
0
0
0
0
19
10
10
19
19
10
0
10
% S
% Thr:
10
10
37
0
0
0
0
46
10
0
10
10
0
0
0
% T
% Val:
0
19
10
46
10
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
10
10
0
0
0
0
46
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _