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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLC All Species: 0
Human Site: T111 Identified Species: 0
UniProt: Q05315 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05315 NP_001819.2 142 16481 T111 V N G Q S S Y T F D H R I K P
Chimpanzee Pan troglodytes XP_512655 142 16566 A111 V N G E Y I Y A F V H R I P P
Rhesus Macaque Macaca mulatta XP_001087874 216 24874 N188 V N G Q A Y Y N F N H R I P V
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P97400 68 8018 Q41 S R V N G A W Q Y E V T C H N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509441 131 14640 F106 D H R E F C S F A H R L D V E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.5 53.2 N.A. N.A. 35.2 N.A. N.A. 29.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 67.6 57.4 N.A. N.A. 38.7 N.A. N.A. 48.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 60 N.A. N.A. 0 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 73.3 N.A. N.A. 26.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 20 20 0 20 20 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 20 0 0 0 0 0 0 20 0 0 % C
% Asp: 20 0 0 0 0 0 0 0 0 20 0 0 20 0 0 % D
% Glu: 0 0 0 40 0 0 0 0 0 20 0 0 0 0 20 % E
% Phe: 0 0 0 0 20 0 0 20 60 0 0 0 0 0 0 % F
% Gly: 0 0 60 0 20 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 20 0 0 0 0 0 0 0 20 60 0 0 20 0 % H
% Ile: 0 0 0 0 0 20 0 0 0 0 0 0 60 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 60 0 20 0 0 0 20 0 20 0 0 0 0 20 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 40 40 % P
% Gln: 0 0 0 40 0 0 0 20 0 0 0 0 0 0 0 % Q
% Arg: 0 20 20 0 0 0 0 0 0 0 20 60 0 0 0 % R
% Ser: 20 0 0 0 20 20 20 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 20 0 0 0 20 0 0 0 % T
% Val: 60 0 20 0 0 0 0 0 0 20 20 0 0 20 20 % V
% Trp: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 20 20 60 0 20 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _