KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLC
All Species:
7.27
Human Site:
Y100
Identified Species:
40
UniProt:
Q05315
Number Species:
4
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05315
NP_001819.2
142
16481
Y100
I
S
V
L
P
D
K
Y
Q
V
M
V
N
G
Q
Chimpanzee
Pan troglodytes
XP_512655
142
16566
Y100
I
Y
V
C
H
N
E
Y
E
V
K
V
N
G
E
Rhesus Macaque
Macaca mulatta
XP_001087874
216
24874
Y177
I
L
V
L
E
D
K
Y
Q
V
M
V
N
G
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97400
68
8018
V30
R
V
Y
F
G
H
W
V
V
M
N
S
R
V
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509441
131
14640
K95
K
V
E
E
N
C
F
K
V
F
V
D
H
R
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.5
53.2
N.A.
N.A.
35.2
N.A.
N.A.
29.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.6
57.4
N.A.
N.A.
38.7
N.A.
N.A.
48.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
86.6
N.A.
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
86.6
N.A.
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
20
0
20
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
40
0
0
0
0
0
20
0
0
0
% D
% Glu:
0
0
20
20
20
0
20
0
20
0
0
0
0
0
40
% E
% Phe:
0
0
0
20
0
0
20
0
0
20
0
0
0
0
0
% F
% Gly:
0
0
0
0
20
0
0
0
0
0
0
0
0
60
0
% G
% His:
0
0
0
0
20
20
0
0
0
0
0
0
20
0
0
% H
% Ile:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
0
0
0
0
0
40
20
0
0
20
0
0
0
0
% K
% Leu:
0
20
0
40
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
20
40
0
0
0
0
% M
% Asn:
0
0
0
0
20
20
0
0
0
0
20
0
60
0
20
% N
% Pro:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
40
% Q
% Arg:
20
0
0
0
0
0
0
0
0
0
0
0
20
20
0
% R
% Ser:
0
20
0
0
0
0
0
0
0
0
0
20
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
40
60
0
0
0
0
20
40
60
20
60
0
20
0
% V
% Trp:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
20
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _