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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAD2 All Species: 35.45
Human Site: Y433 Identified Species: 65
UniProt: Q05329 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05329 NP_000809.1 585 65411 Y433 L F Q Q D K H Y D L S Y D T G
Chimpanzee Pan troglodytes Q5IS68 594 66879 Y442 L F Q P D K Q Y D V S Y D T G
Rhesus Macaque Macaca mulatta XP_001101800 540 60175 V409 L Q C S A L L V R E E G L M Q
Dog Lupus familis XP_541080 543 61384 T401 D F D T G D K T I Q C G R H V
Cat Felis silvestris
Mouse Mus musculus P48320 585 65206 Y433 L F Q Q D K H Y D L S Y D T G
Rat Rattus norvegicus Q05683 585 65384 Y433 L F Q Q D K H Y D L S Y D T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506641 568 63961 Y416 L F Q Q D K H Y D L S Y D T G
Chicken Gallus gallus XP_418596 610 68572 Y458 L F Q Q D K H Y D L S Y D T G
Frog Xenopus laevis NP_001079270 563 64077 Y411 L F Q Q D K Q Y D V S Y D T G
Zebra Danio Brachydanio rerio NP_001017708 583 65440 Y431 L F Q Q D K H Y D L Q Y D T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20228 510 57801 F379 C G R H N D I F K L W L Q W R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784856 614 68930 Y459 L F Q Q D K H Y D V S F D T G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M0G4 545 60786 W407 T V V N Y K D W Q I S L S R R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.3 90.4 55.2 N.A. 95.7 96 N.A. 88.7 79.3 54.3 78.4 N.A. 47.5 N.A. N.A. 51.4
Protein Similarity: 100 79.6 91.1 73.3 N.A. 97.2 97.7 N.A. 93.1 84.4 69.4 88.8 N.A. 63.5 N.A. N.A. 69.5
P-Site Identity: 100 80 6.6 6.6 N.A. 100 100 N.A. 100 100 86.6 93.3 N.A. 6.6 N.A. N.A. 86.6
P-Site Similarity: 100 86.6 6.6 6.6 N.A. 100 100 N.A. 100 100 93.3 93.3 N.A. 26.6 N.A. N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 8 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 8 0 8 0 70 16 8 0 70 0 0 0 70 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % E
% Phe: 0 77 0 0 0 0 0 8 0 0 0 8 0 0 0 % F
% Gly: 0 8 0 0 8 0 0 0 0 0 0 16 0 0 70 % G
% His: 0 0 0 8 0 0 54 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 8 0 8 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 77 8 0 8 0 0 0 0 0 0 % K
% Leu: 77 0 0 0 0 8 8 0 0 54 0 16 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 70 62 0 0 16 0 8 8 8 0 8 0 8 % Q
% Arg: 0 0 8 0 0 0 0 0 8 0 0 0 8 8 16 % R
% Ser: 0 0 0 8 0 0 0 0 0 0 70 0 8 0 0 % S
% Thr: 8 0 0 8 0 0 0 8 0 0 0 0 0 70 0 % T
% Val: 0 8 8 0 0 0 0 8 0 24 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 8 0 0 8 0 % W
% Tyr: 0 0 0 0 8 0 0 70 0 0 0 62 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _