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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTK2
All Species:
36.36
Human Site:
Y194
Identified Species:
80
UniProt:
Q05397
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05397
NP_005598.3
1052
119233
Y194
A
L
E
K
K
S
N
Y
E
V
L
E
K
D
V
Chimpanzee
Pan troglodytes
XP_001147699
1096
124125
Y238
A
L
E
K
K
S
N
Y
E
V
L
E
K
D
V
Rhesus Macaque
Macaca mulatta
XP_001093060
1097
123900
Y238
A
L
E
K
K
S
N
Y
E
V
L
E
K
D
V
Dog
Lupus familis
XP_856301
1068
120990
Y194
A
L
E
K
K
S
N
Y
E
V
L
E
K
D
V
Cat
Felis silvestris
Mouse
Mus musculus
P34152
1090
123518
Y194
A
L
E
K
K
S
N
Y
E
V
L
E
K
D
V
Rat
Rattus norvegicus
O35346
1055
119698
Y194
A
L
E
K
K
S
N
Y
E
V
L
E
K
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510393
1059
119735
Y194
A
L
E
K
K
S
N
Y
E
V
L
E
K
D
V
Chicken
Gallus gallus
Q00944
1053
119189
Y194
A
L
E
K
K
S
N
Y
E
V
L
E
K
D
V
Frog
Xenopus laevis
Q91738
1068
121137
Y194
A
L
E
K
K
S
N
Y
E
V
L
E
K
D
V
Zebra Danio
Brachydanio rerio
O13147
500
55892
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120873
1165
130750
L199
A
L
D
K
K
S
N
L
E
Y
L
E
R
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
93.2
95.4
N.A.
93.7
96.6
N.A.
92.6
94.6
88.7
20.7
N.A.
N.A.
37.5
N.A.
N.A.
Protein Similarity:
100
95.8
93.8
97
N.A.
95.1
98.5
N.A.
95.3
97.6
93.9
31.6
N.A.
N.A.
54.9
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
0
N.A.
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
0
N.A.
N.A.
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
91
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
82
0
% D
% Glu:
0
0
82
0
0
0
0
0
91
0
0
91
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
91
91
0
0
0
0
0
0
0
82
0
0
% K
% Leu:
0
91
0
0
0
0
0
10
0
0
91
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
91
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
91
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
82
0
0
0
0
91
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _