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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPE All Species: 1.21
Human Site: S272 Identified Species: 3.81
UniProt: Q05469 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05469 NP_005348.2 1076 116598 S272 K S G Y K V M S G Y S G T S P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533655 889 96890 R131 S Q S Q R H Y R D T A S R L T
Cat Felis silvestris
Mouse Mus musculus P54310 759 83329
Rat Rattus norvegicus P15304 1068 116793 G271 P D C G K M S G Y G G K L P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001124413 832 91875 M75 A N G Y R S L M K V V L S C T
Zebra Danio Brachydanio rerio XP_686139 538 59103
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397143 733 81786
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194738 827 91195 T70 E A D A M R P T V E A L E R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 66.6 N.A. 60.3 71.9 N.A. N.A. N.A. 44.3 33.7 N.A. N.A. 26 N.A. 32.1
Protein Similarity: 100 N.A. N.A. 72.6 N.A. 64.5 79.6 N.A. N.A. N.A. 55.1 43 N.A. N.A. 40.7 N.A. 46.7
P-Site Identity: 100 N.A. N.A. 0 N.A. 0 6.6 N.A. N.A. N.A. 13.3 0 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 N.A. N.A. 13.3 N.A. 0 13.3 N.A. N.A. N.A. 40 0 N.A. N.A. 0 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 0 13 0 0 0 0 0 0 25 0 0 0 0 % A
% Cys: 0 0 13 0 0 0 0 0 0 0 0 0 0 13 0 % C
% Asp: 0 13 13 0 0 0 0 0 13 0 0 0 0 0 0 % D
% Glu: 13 0 0 0 0 0 0 0 0 13 0 0 13 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 25 13 0 0 0 13 13 13 13 13 0 0 0 % G
% His: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 13 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % I
% Lys: 13 0 0 0 25 0 0 0 13 0 0 13 0 0 0 % K
% Leu: 0 0 0 0 0 0 13 0 0 0 0 25 13 13 0 % L
% Met: 0 0 0 0 13 13 13 13 0 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 13 0 0 0 0 0 13 0 0 0 0 0 0 13 13 % P
% Gln: 0 13 0 13 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 25 13 0 13 0 0 0 0 13 13 0 % R
% Ser: 13 13 13 0 0 13 13 13 0 0 13 13 13 13 0 % S
% Thr: 0 0 0 0 0 0 0 13 0 13 0 0 13 0 25 % T
% Val: 0 0 0 0 0 13 0 0 13 13 13 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 25 0 0 13 0 13 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _