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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPE All Species: 11.21
Human Site: S553 Identified Species: 35.24
UniProt: Q05469 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05469 NP_005348.2 1076 116598 S553 T E M E V L S S L A N M A S A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533655 889 96890 S392 T E I E V L S S L A N M A S A
Cat Felis silvestris
Mouse Mus musculus P54310 759 83329 R262 N M A S T T V R V S R L L S L
Rat Rattus norvegicus P15304 1068 116793 S552 T E I E V L S S L A N M A S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001124413 832 91875 S335 S L D L R L R S R P A P L S P
Zebra Danio Brachydanio rerio XP_686139 538 59103 T41 Q R L V D A M T I I Q E H A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397143 733 81786 L236 A N S V K Y M L D P E I R A R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194738 827 91195 R330 R L L C F V E R E G Q G W L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 66.6 N.A. 60.3 71.9 N.A. N.A. N.A. 44.3 33.7 N.A. N.A. 26 N.A. 32.1
Protein Similarity: 100 N.A. N.A. 72.6 N.A. 64.5 79.6 N.A. N.A. N.A. 55.1 43 N.A. N.A. 40.7 N.A. 46.7
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 6.6 86.6 N.A. N.A. N.A. 20 0 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 N.A. N.A. 100 N.A. 26.6 93.3 N.A. N.A. N.A. 26.6 26.6 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 13 0 0 13 0 0 0 38 13 0 38 25 25 % A
% Cys: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 0 13 0 0 0 13 0 0 0 0 0 0 % D
% Glu: 0 38 0 38 0 0 13 0 13 0 13 13 0 0 0 % E
% Phe: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 13 0 13 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % H
% Ile: 0 0 25 0 0 0 0 0 13 13 0 13 0 0 0 % I
% Lys: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 25 25 13 0 50 0 13 38 0 0 13 25 13 13 % L
% Met: 0 13 13 0 0 0 25 0 0 0 0 38 0 0 0 % M
% Asn: 13 13 0 0 0 0 0 0 0 0 38 0 0 0 13 % N
% Pro: 0 0 0 0 0 0 0 0 0 25 0 13 0 0 13 % P
% Gln: 13 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % Q
% Arg: 13 13 0 0 13 0 13 25 13 0 13 0 13 0 25 % R
% Ser: 13 0 13 13 0 0 38 50 0 13 0 0 0 63 0 % S
% Thr: 38 0 0 0 13 13 0 13 0 0 0 0 0 0 13 % T
% Val: 0 0 0 25 38 13 13 0 13 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % W
% Tyr: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _