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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPE All Species: 5.45
Human Site: T659 Identified Species: 17.14
UniProt: Q05469 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05469 NP_005348.2 1076 116598 T659 G G G F V A Q T S R S H E P Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533655 889 96890 T498 G G G F V A Q T S K S H E P Y
Cat Felis silvestris
Mouse Mus musculus P54310 759 83329 W368 H E P Y L K N W A Q E L G V P
Rat Rattus norvegicus P15304 1068 116793 S658 G G F V A Q T S K S H E P Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001124413 832 91875 I441 L R A A S V G I R M P D G I M
Zebra Danio Brachydanio rerio XP_686139 538 59103 E147 H G N L F F Q E E S G L S Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397143 733 81786 G342 G V G G E L H G L S N E L I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194738 827 91195 G436 V K N A P Y L G S T G E H I C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 66.6 N.A. 60.3 71.9 N.A. N.A. N.A. 44.3 33.7 N.A. N.A. 26 N.A. 32.1
Protein Similarity: 100 N.A. N.A. 72.6 N.A. 64.5 79.6 N.A. N.A. N.A. 55.1 43 N.A. N.A. 40.7 N.A. 46.7
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 0 13.3 N.A. N.A. N.A. 0 13.3 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 26.6 20 N.A. N.A. N.A. 0 13.3 N.A. N.A. 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 25 13 25 0 0 13 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % D
% Glu: 0 13 0 0 13 0 0 13 13 0 13 38 25 0 0 % E
% Phe: 0 0 13 25 13 13 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 50 38 13 0 0 13 25 0 0 25 0 25 0 0 % G
% His: 25 0 0 0 0 0 13 0 0 0 13 25 13 0 0 % H
% Ile: 0 0 0 0 0 0 0 13 0 0 0 0 0 38 13 % I
% Lys: 0 13 0 0 0 13 0 0 13 13 0 0 0 0 0 % K
% Leu: 13 0 0 13 13 13 13 0 13 0 0 25 13 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 13 % M
% Asn: 0 0 25 0 0 0 13 0 0 0 13 0 0 0 0 % N
% Pro: 0 0 13 0 13 0 0 0 0 0 13 0 13 25 13 % P
% Gln: 0 0 0 0 0 13 38 0 0 13 0 0 0 13 0 % Q
% Arg: 0 13 0 0 0 0 0 0 13 13 0 0 0 0 0 % R
% Ser: 0 0 0 0 13 0 0 13 38 38 25 0 13 0 13 % S
% Thr: 0 0 0 0 0 0 13 25 0 13 0 0 0 0 0 % T
% Val: 13 13 0 13 25 13 0 0 0 0 0 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 13 0 13 0 0 0 0 0 0 0 13 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _