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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPE All Species: 3.64
Human Site: T875 Identified Species: 11.43
UniProt: Q05469 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05469 NP_005348.2 1076 116598 T875 T D S L K N L T L R D L S L R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533655 889 96890 P711 S E A A L A Q P E G L L G T D
Cat Felis silvestris
Mouse Mus musculus P54310 759 83329 K581 T L K K L T I K D L S N S E P
Rat Rattus norvegicus P15304 1068 116793 E873 E A A L A Q P E G L L G T D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001124413 832 91875 S654 F F L S E T E S D S D T S G Q
Zebra Danio Brachydanio rerio XP_686139 538 59103 A360 F H G G G F V A Q T S K S H E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397143 733 81786 T555 D S T L N S V T L T E A D G M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194738 827 91195 N649 F D P S H P P N T A D H P N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 66.6 N.A. 60.3 71.9 N.A. N.A. N.A. 44.3 33.7 N.A. N.A. 26 N.A. 32.1
Protein Similarity: 100 N.A. N.A. 72.6 N.A. 64.5 79.6 N.A. N.A. N.A. 55.1 43 N.A. N.A. 40.7 N.A. 46.7
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 13.3 6.6 N.A. N.A. N.A. 13.3 6.6 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 20 20 N.A. N.A. N.A. 33.3 13.3 N.A. N.A. 46.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 25 13 13 13 0 13 0 13 0 13 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 25 0 0 0 0 0 0 25 0 38 0 13 13 13 % D
% Glu: 13 13 0 0 13 0 13 13 13 0 13 0 0 13 13 % E
% Phe: 38 13 0 0 0 13 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 13 13 13 0 0 0 13 13 0 13 13 25 0 % G
% His: 0 13 0 0 13 0 0 0 0 0 0 13 0 13 0 % H
% Ile: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 13 13 13 0 0 13 0 0 0 13 0 0 0 % K
% Leu: 0 13 13 38 25 0 13 0 25 25 25 25 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % M
% Asn: 0 0 0 0 13 13 0 13 0 0 0 13 0 13 0 % N
% Pro: 0 0 13 0 0 13 25 13 0 0 0 0 13 0 13 % P
% Gln: 0 0 0 0 0 13 13 0 13 0 0 0 0 0 13 % Q
% Arg: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 13 % R
% Ser: 13 13 13 25 0 13 0 13 0 13 25 0 50 0 25 % S
% Thr: 25 0 13 0 0 25 0 25 13 25 0 13 13 13 0 % T
% Val: 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _