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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIPE
All Species:
4.55
Human Site:
Y741
Identified Species:
14.29
UniProt:
Q05469
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05469
NP_005348.2
1076
116598
Y741
V
A
L
R
A
A
A
Y
G
V
R
V
P
D
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533655
889
96890
A577
C
F
T
V
S
L
R
A
A
A
Y
G
V
R
V
Cat
Felis silvestris
Mouse
Mus musculus
P54310
759
83329
I447
G
V
R
V
P
D
G
I
M
A
A
Y
P
V
T
Rat
Rattus norvegicus
P15304
1068
116793
Y739
V
S
L
R
A
A
A
Y
G
V
R
V
P
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001124413
832
91875
R520
A
L
F
L
R
D
I
R
H
G
A
T
S
W
L
Zebra Danio
Brachydanio rerio
XP_686139
538
59103
G226
A
I
D
P
E
L
R
G
Q
E
Y
E
R
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397143
733
81786
I421
L
G
S
T
A
Q
K
I
L
L
A
G
D
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194738
827
91195
E515
S
A
Y
V
D
L
K
E
E
F
M
T
E
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
66.6
N.A.
60.3
71.9
N.A.
N.A.
N.A.
44.3
33.7
N.A.
N.A.
26
N.A.
32.1
Protein Similarity:
100
N.A.
N.A.
72.6
N.A.
64.5
79.6
N.A.
N.A.
N.A.
55.1
43
N.A.
N.A.
40.7
N.A.
46.7
P-Site Identity:
100
N.A.
N.A.
0
N.A.
6.6
93.3
N.A.
N.A.
N.A.
0
0
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
6.6
N.A.
6.6
100
N.A.
N.A.
N.A.
0
0
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
25
0
0
38
25
25
13
13
25
38
0
0
0
13
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
13
25
0
0
0
0
0
0
13
25
0
% D
% Glu:
0
0
0
0
13
0
0
13
13
13
0
13
13
13
0
% E
% Phe:
0
13
13
0
0
0
0
0
0
13
0
0
0
0
0
% F
% Gly:
13
13
0
0
0
0
13
13
25
13
0
25
0
0
25
% G
% His:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
0
13
25
0
0
0
0
0
13
0
% I
% Lys:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
13
% K
% Leu:
13
13
25
13
0
38
0
0
13
13
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
13
13
0
0
0
0
0
0
0
38
0
0
% P
% Gln:
0
0
0
0
0
13
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
13
25
13
0
25
13
0
0
25
0
13
13
0
% R
% Ser:
13
13
13
0
13
0
0
0
0
0
0
0
13
13
0
% S
% Thr:
0
0
13
13
0
0
0
0
0
0
0
25
0
0
25
% T
% Val:
25
13
0
38
0
0
0
0
0
25
0
25
13
13
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% W
% Tyr:
0
0
13
0
0
0
0
25
0
0
25
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _