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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCD
All Species:
13.03
Human Site:
S130
Identified Species:
22.05
UniProt:
Q05655
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05655
NP_006245.2
676
77505
S130
E
D
V
D
C
K
Q
S
M
R
S
E
D
E
A
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
M131
E
M
S
D
T
K
D
M
N
E
F
E
T
E
G
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
S594
E
D
V
D
C
K
Q
S
M
R
S
E
D
E
A
Dog
Lupus familis
XP_849292
706
81555
M131
E
M
S
D
T
K
D
M
S
E
F
E
T
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P28867
674
77529
S130
E
D
G
D
C
K
Q
S
M
R
S
E
E
E
A
Rat
Rattus norvegicus
P09215
673
77502
S130
E
D
G
D
C
K
Q
S
M
R
S
E
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
L131
E
M
S
D
T
K
E
L
S
E
F
E
T
E
G
Chicken
Gallus gallus
NP_001006133
699
80179
R128
F
L
E
D
A
D
C
R
Q
S
M
R
E
E
E
Frog
Xenopus laevis
NP_001084460
683
78181
Q129
L
E
D
A
D
L
K
Q
S
I
R
E
D
E
G
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
K105
V
F
P
C
V
P
E
K
P
G
M
P
C
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83099
671
76314
V116
G
G
V
T
G
G
G
V
Y
V
D
R
R
T
R
Honey Bee
Apis mellifera
XP_394743
624
71014
Q117
L
V
A
K
F
F
S
Q
P
T
F
C
A
F
C
Nematode Worm
Caenorhab. elegans
P34722
704
80280
I137
D
D
H
P
V
E
D
I
M
T
S
R
S
N
S
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
G110
E
F
I
W
G
L
V
G
T
Q
G
Y
R
C
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
58.5
63.5
N.A.
90.3
89.5
N.A.
63.7
82.4
81.4
33.2
N.A.
46.7
45.2
47.1
49.1
Protein Similarity:
100
76.7
59
77.6
N.A.
95.4
95.2
N.A.
77.9
89.9
89.5
50.8
N.A.
61.9
61.3
64.7
63.6
P-Site Identity:
100
33.3
100
33.3
N.A.
86.6
86.6
N.A.
33.3
13.3
20
0
N.A.
6.6
0
20
6.6
P-Site Similarity:
100
33.3
100
33.3
N.A.
93.3
93.3
N.A.
40
20
33.3
6.6
N.A.
6.6
0
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
0
0
0
0
0
8
0
29
% A
% Cys:
0
0
0
8
29
0
8
0
0
0
0
8
8
8
8
% C
% Asp:
8
36
8
58
8
8
22
0
0
0
8
0
22
0
0
% D
% Glu:
58
8
8
0
0
8
15
0
0
22
0
58
22
65
8
% E
% Phe:
8
15
0
0
8
8
0
0
0
0
29
0
0
8
0
% F
% Gly:
8
8
15
0
15
8
8
8
0
8
8
0
0
0
36
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
50
8
8
0
0
0
0
0
0
0
% K
% Leu:
15
8
0
0
0
15
0
8
0
0
0
0
0
0
0
% L
% Met:
0
22
0
0
0
0
0
15
36
0
15
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
0
8
8
0
8
0
0
15
0
0
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
29
15
8
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
29
8
22
15
0
8
% R
% Ser:
0
0
22
0
0
0
8
29
22
8
36
0
8
0
8
% S
% Thr:
0
0
0
8
22
0
0
0
8
15
0
0
22
8
0
% T
% Val:
8
8
22
0
15
0
8
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _