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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCD
All Species:
16.97
Human Site:
T333
Identified Species:
28.72
UniProt:
Q05655
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05655
NP_006245.2
676
77505
T333
D
M
Q
D
N
S
G
T
Y
G
K
I
W
E
G
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
L336
R
P
P
C
L
P
T
L
G
K
R
E
P
Q
G
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
T797
D
S
Q
D
N
S
G
T
Y
G
K
I
W
E
G
Dog
Lupus familis
XP_849292
706
81555
P336
R
L
P
C
V
P
A
P
G
K
K
E
P
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
P28867
674
77529
T331
D
I
L
D
N
N
G
T
Y
G
K
I
W
E
G
Rat
Rattus norvegicus
P09215
673
77502
T331
D
I
P
D
N
N
G
T
Y
G
K
I
W
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
R357
L
P
P
E
E
V
M
R
P
E
I
A
P
E
P
Chicken
Gallus gallus
NP_001006133
699
80179
Y331
D
T
G
D
N
S
Q
Y
D
K
L
W
E
G
S
Frog
Xenopus laevis
NP_001084460
683
78181
Y332
P
N
A
P
D
N
Q
Y
D
K
L
W
E
G
I
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
T268
L
L
V
R
L
K
K
T
E
R
I
Y
A
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83099
671
76314
F319
T
S
Y
T
Y
S
Q
F
Q
K
S
G
R
F
T
Honey Bee
Apis mellifera
XP_394743
624
71014
H278
R
N
S
D
S
S
D
H
F
P
S
G
R
I
T
Nematode Worm
Caenorhab. elegans
P34722
704
80280
I359
T
D
E
Y
M
D
N
I
W
G
G
G
D
G
P
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
S271
Q
K
V
L
G
K
G
S
F
G
K
V
M
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
58.5
63.5
N.A.
90.3
89.5
N.A.
63.7
82.4
81.4
33.2
N.A.
46.7
45.2
47.1
49.1
Protein Similarity:
100
76.7
59
77.6
N.A.
95.4
95.2
N.A.
77.9
89.9
89.5
50.8
N.A.
61.9
61.3
64.7
63.6
P-Site Identity:
100
6.6
93.3
13.3
N.A.
80
80
N.A.
6.6
26.6
0
6.6
N.A.
6.6
13.3
6.6
20
P-Site Similarity:
100
20
93.3
26.6
N.A.
93.3
93.3
N.A.
13.3
26.6
13.3
13.3
N.A.
6.6
26.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
0
0
8
8
0
8
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
36
8
0
43
8
8
8
0
15
0
0
0
8
0
0
% D
% Glu:
0
0
8
8
8
0
0
0
8
8
0
15
15
36
0
% E
% Phe:
0
0
0
0
0
0
0
8
15
0
0
0
0
8
0
% F
% Gly:
0
0
8
0
8
0
36
0
15
43
8
22
0
22
43
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
0
0
0
8
0
0
15
29
0
8
8
% I
% Lys:
0
8
0
0
0
15
8
0
0
36
43
0
0
0
8
% K
% Leu:
15
15
8
8
15
0
0
8
0
0
15
0
0
8
0
% L
% Met:
0
8
0
0
8
0
8
0
0
0
0
0
8
8
0
% M
% Asn:
0
15
0
0
36
22
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
15
29
8
0
15
0
8
8
8
0
0
22
0
15
% P
% Gln:
8
0
15
0
0
0
22
0
8
0
0
0
0
15
0
% Q
% Arg:
22
0
0
8
0
0
0
8
0
8
8
0
15
0
0
% R
% Ser:
0
15
8
0
8
36
0
8
0
0
15
0
0
0
8
% S
% Thr:
15
8
0
8
0
0
8
36
0
0
0
0
0
0
15
% T
% Val:
0
0
15
0
8
8
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
15
29
0
0
% W
% Tyr:
0
0
8
8
8
0
0
15
29
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _