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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCD
All Species:
35.15
Human Site:
T451
Identified Species:
59.49
UniProt:
Q05655
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05655
NP_006245.2
676
77505
T451
R
F
E
L
Y
R
A
T
F
Y
A
A
E
I
M
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
T482
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
T915
R
F
E
L
Y
R
A
T
F
Y
A
A
E
I
I
Dog
Lupus familis
XP_849292
706
81555
T482
K
F
D
L
S
R
A
T
F
Y
A
A
E
I
I
Cat
Felis silvestris
Mouse
Mus musculus
P28867
674
77529
T449
R
F
E
L
Y
R
A
T
F
Y
A
A
E
I
I
Rat
Rattus norvegicus
P09215
673
77502
T449
R
F
E
L
Y
R
A
T
F
Y
A
A
E
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
T484
K
F
E
L
V
R
A
T
F
Y
A
A
E
I
I
Chicken
Gallus gallus
NP_001006133
699
80179
T459
R
F
D
L
Y
R
A
T
F
Y
G
A
E
I
L
Frog
Xenopus laevis
NP_001084460
683
78181
T458
R
F
D
L
Y
R
A
T
F
Y
A
S
E
I
I
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
V376
R
D
L
K
L
D
N
V
L
L
D
S
E
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83099
671
76314
R445
R
F
S
E
E
R
A
R
F
Y
G
A
E
I
I
Honey Bee
Apis mellifera
XP_394743
624
71014
R404
R
F
P
E
P
R
A
R
F
Y
A
A
E
I
W
Nematode Worm
Caenorhab. elegans
P34722
704
80280
R477
K
F
D
E
A
R
T
R
F
Y
A
C
E
I
V
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
G380
L
Q
F
L
H
K
R
G
I
I
Y
R
D
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
58.5
63.5
N.A.
90.3
89.5
N.A.
63.7
82.4
81.4
33.2
N.A.
46.7
45.2
47.1
49.1
Protein Similarity:
100
76.7
59
77.6
N.A.
95.4
95.2
N.A.
77.9
89.9
89.5
50.8
N.A.
61.9
61.3
64.7
63.6
P-Site Identity:
100
73.3
93.3
73.3
N.A.
93.3
93.3
N.A.
80
80
80
13.3
N.A.
60
66.6
46.6
6.6
P-Site Similarity:
100
93.3
100
93.3
N.A.
100
100
N.A.
93.3
93.3
100
20
N.A.
66.6
66.6
66.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
79
0
0
0
72
72
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
36
0
0
8
0
0
0
0
8
0
8
0
0
% D
% Glu:
0
0
36
22
8
0
0
0
0
0
0
0
93
0
0
% E
% Phe:
0
86
8
0
0
0
0
0
86
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
15
0
0
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
8
8
0
0
0
86
58
% I
% Lys:
29
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% K
% Leu:
8
0
8
72
8
0
0
0
8
8
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
65
0
0
0
0
86
8
22
0
0
0
8
0
0
0
% R
% Ser:
0
0
8
0
15
0
0
0
0
0
0
15
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
65
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
43
0
0
0
0
86
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _