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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCD
All Species:
17.27
Human Site:
T594
Identified Species:
29.23
UniProt:
Q05655
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05655
NP_006245.2
676
77505
T594
P
T
K
R
L
G
V
T
G
N
I
K
I
H
P
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
R625
P
E
K
R
L
G
V
R
G
D
I
R
Q
H
P
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
T1058
P
T
K
R
L
G
V
T
G
N
I
K
I
H
P
Dog
Lupus familis
XP_849292
706
81555
R625
P
E
K
R
L
G
V
R
G
D
I
R
Q
H
P
Cat
Felis silvestris
Mouse
Mus musculus
P28867
674
77529
T592
P
D
K
R
L
G
V
T
G
N
I
R
I
H
P
Rat
Rattus norvegicus
P09215
673
77502
T592
P
A
K
R
L
G
V
T
G
N
I
R
L
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
K627
P
E
R
R
L
G
V
K
G
N
I
R
Q
H
A
Chicken
Gallus gallus
NP_001006133
699
80179
T617
P
T
R
R
L
G
V
T
G
N
I
R
D
H
P
Frog
Xenopus laevis
NP_001084460
683
78181
V601
P
F
K
R
L
G
V
V
G
N
I
K
L
H
P
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
F505
G
C
H
P
Q
T
G
F
A
D
I
M
A
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83099
671
76314
Q588
Y
T
K
R
I
G
S
Q
Y
S
P
A
G
D
I
Honey Bee
Apis mellifera
XP_394743
624
71014
H547
S
G
K
R
L
P
G
H
E
I
A
L
H
S
F
Nematode Worm
Caenorhab. elegans
P34722
704
80280
P621
P
N
T
R
L
G
M
P
E
C
P
D
G
P
I
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
K506
P
E
V
R
L
G
V
K
G
D
V
R
A
H
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
58.5
63.5
N.A.
90.3
89.5
N.A.
63.7
82.4
81.4
33.2
N.A.
46.7
45.2
47.1
49.1
Protein Similarity:
100
76.7
59
77.6
N.A.
95.4
95.2
N.A.
77.9
89.9
89.5
50.8
N.A.
61.9
61.3
64.7
63.6
P-Site Identity:
100
66.6
100
66.6
N.A.
86.6
80
N.A.
60
80
80
20
N.A.
26.6
20
26.6
46.6
P-Site Similarity:
100
80
100
80
N.A.
93.3
93.3
N.A.
73.3
93.3
86.6
26.6
N.A.
40
20
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
8
0
8
8
15
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
29
0
8
8
8
0
% D
% Glu:
0
29
0
0
0
0
0
0
15
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
8
8
0
0
0
86
15
0
72
0
0
0
15
0
0
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
8
79
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
72
0
22
0
15
% I
% Lys:
0
0
65
0
0
0
0
15
0
0
0
22
0
0
0
% K
% Leu:
0
0
0
0
86
0
0
0
0
0
0
8
15
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
50
0
0
0
0
0
% N
% Pro:
79
0
0
8
0
8
0
8
0
0
15
0
0
8
65
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
0
0
22
0
8
% Q
% Arg:
0
0
15
93
0
0
0
15
0
0
0
50
0
0
0
% R
% Ser:
8
0
0
0
0
0
8
0
0
8
0
0
0
8
0
% S
% Thr:
0
29
8
0
0
8
0
36
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
72
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _