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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKCD All Species: 37.88
Human Site: Y52 Identified Species: 64.1
UniProt: Q05655 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05655 NP_006245.2 676 77505 Y52 V Q K K P T M Y P E W K S T F
Chimpanzee Pan troglodytes XP_001147999 706 81847 Y53 I Q K K P T M Y P P W D S T F
Rhesus Macaque Macaca mulatta XP_001083320 1140 127261 Y516 V Q K K P T M Y P E W K S T F
Dog Lupus familis XP_849292 706 81555 Y53 I Q K K P T M Y P P W D S T F
Cat Felis silvestris
Mouse Mus musculus P28867 674 77529 Y52 V Q K K P T M Y P E W K T T F
Rat Rattus norvegicus P09215 673 77502 Y52 V Q K K P T M Y P E W K S T F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509836 708 81415 Y53 V Q K K P T M Y P P W D S T F
Chicken Gallus gallus NP_001006133 699 80179 Y52 I Q R K P T M Y P E W K S T F
Frog Xenopus laevis NP_001084460 683 78181 Y52 V Q K K P T M Y P D W K S V F
Zebra Danio Brachydanio rerio Q90XF2 588 67303 L43 P S I S Y E G L C N E V R D M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P83099 671 76314 L48 S S G A G S G L S G A S G A S
Honey Bee Apis mellifera XP_394743 624 71014 L52 P I L N P T D L P P A S S I G
Nematode Worm Caenorhab. elegans P34722 704 80280 Y57 V Q K K K T L Y P E W E K C W
Sea Urchin Strong. purpuratus XP_787505 585 66691 V46 G G D P M N S V R S T V S H H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.7 58.5 63.5 N.A. 90.3 89.5 N.A. 63.7 82.4 81.4 33.2 N.A. 46.7 45.2 47.1 49.1
Protein Similarity: 100 76.7 59 77.6 N.A. 95.4 95.2 N.A. 77.9 89.9 89.5 50.8 N.A. 61.9 61.3 64.7 63.6
P-Site Identity: 100 80 100 80 N.A. 93.3 100 N.A. 86.6 86.6 86.6 0 N.A. 0 26.6 60 6.6
P-Site Similarity: 100 86.6 100 86.6 N.A. 100 100 N.A. 86.6 100 93.3 0 N.A. 6.6 26.6 80 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 0 15 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % C
% Asp: 0 0 8 0 0 0 8 0 0 8 0 22 0 8 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 43 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65 % F
% Gly: 8 8 8 0 8 0 15 0 0 8 0 0 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % H
% Ile: 22 8 8 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 65 72 8 0 0 0 0 0 0 43 8 0 0 % K
% Leu: 0 0 8 0 0 0 8 22 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 8 0 65 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 8 0 8 0 0 0 8 0 0 0 0 0 % N
% Pro: 15 0 0 8 72 0 0 0 79 29 0 0 0 0 0 % P
% Gln: 0 72 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 8 0 0 0 8 0 0 % R
% Ser: 8 15 0 8 0 8 8 0 8 8 0 15 72 0 8 % S
% Thr: 0 0 0 0 0 79 0 0 0 0 8 0 8 58 0 % T
% Val: 50 0 0 0 0 0 0 8 0 0 0 15 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 72 0 0 0 8 % W
% Tyr: 0 0 0 0 8 0 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _