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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCD
All Species:
47.27
Human Site:
Y525
Identified Species:
80
UniProt:
Q05655
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05655
NP_006245.2
676
77505
Y525
E
I
L
Q
G
L
K
Y
T
F
S
V
D
W
W
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
Y556
E
I
L
L
G
Q
K
Y
N
H
S
V
D
W
W
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
Y989
E
I
L
Q
G
L
K
Y
T
F
S
V
D
W
W
Dog
Lupus familis
XP_849292
706
81555
Y556
E
I
L
L
G
Q
K
Y
N
H
S
V
D
W
W
Cat
Felis silvestris
Mouse
Mus musculus
P28867
674
77529
Y523
E
I
L
Q
G
L
K
Y
S
F
S
V
D
W
W
Rat
Rattus norvegicus
P09215
673
77502
Y523
E
I
L
Q
G
L
K
Y
S
F
S
V
D
W
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
Y558
E
I
L
L
G
Q
K
Y
N
T
S
V
D
W
W
Chicken
Gallus gallus
NP_001006133
699
80179
Y548
E
I
L
Q
G
L
K
Y
T
F
S
V
D
W
W
Frog
Xenopus laevis
NP_001084460
683
78181
Y532
E
I
L
Q
G
L
K
Y
T
F
S
V
D
W
W
Zebra Danio
Brachydanio rerio
Q90XF2
588
67303
F436
W
A
L
G
V
L
M
F
E
M
M
A
G
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83099
671
76314
Y519
E
I
I
K
G
E
K
Y
N
Q
N
V
D
W
W
Honey Bee
Apis mellifera
XP_394743
624
71014
Y478
E
I
I
K
G
L
K
Y
N
Q
A
V
D
W
W
Nematode Worm
Caenorhab. elegans
P34722
704
80280
Y552
E
I
I
K
G
Q
L
Y
N
E
A
V
D
F
W
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
Y437
E
I
L
K
G
Q
K
Y
A
A
S
V
D
W
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.7
58.5
63.5
N.A.
90.3
89.5
N.A.
63.7
82.4
81.4
33.2
N.A.
46.7
45.2
47.1
49.1
Protein Similarity:
100
76.7
59
77.6
N.A.
95.4
95.2
N.A.
77.9
89.9
89.5
50.8
N.A.
61.9
61.3
64.7
63.6
P-Site Identity:
100
73.3
100
73.3
N.A.
93.3
93.3
N.A.
73.3
100
100
13.3
N.A.
60
66.6
46.6
73.3
P-Site Similarity:
100
73.3
100
73.3
N.A.
100
100
N.A.
73.3
100
100
20
N.A.
80
86.6
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
8
8
15
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% D
% Glu:
93
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
43
0
0
0
8
0
% F
% Gly:
0
0
0
8
93
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% H
% Ile:
0
93
22
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
29
0
0
86
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
79
22
0
58
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
43
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
43
0
36
0
0
0
15
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
0
15
0
72
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
29
8
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
93
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
86
93
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _