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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNB3
All Species:
4.55
Human Site:
T20
Identified Species:
9.09
UniProt:
Q05901
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05901
NP_000740.1
458
52729
T20
G
I
P
S
S
A
T
T
G
F
N
S
I
A
E
Chimpanzee
Pan troglodytes
Q5IS51
468
53049
S38
G
G
A
Q
R
G
L
S
E
P
S
S
I
A
K
Rhesus Macaque
Macaca mulatta
XP_001115605
432
49654
A27
H
D
S
F
T
A
T
A
G
F
S
S
I
A
E
Dog
Lupus familis
XP_539952
528
60300
A90
L
W
I
L
P
G
S
A
G
F
R
S
M
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMN3
464
53093
A26
W
V
T
L
T
A
T
A
G
L
S
S
V
A
E
Rat
Rattus norvegicus
P12391
464
53243
A26
W
V
T
L
T
A
T
A
G
L
S
S
V
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513156
484
55206
S54
C
L
F
N
A
G
I
S
E
P
S
F
I
A
K
Chicken
Gallus gallus
P43679
455
52258
A17
C
W
S
R
S
D
V
A
A
L
G
S
V
V
E
Frog
Xenopus laevis
P05377
457
52088
A15
L
I
F
L
F
I
A
A
G
T
V
F
G
T
D
Zebra Danio
Brachydanio rerio
NP_957514
467
53771
A14
G
I
L
L
V
A
A
A
A
Y
A
T
I
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25162
519
60122
A20
V
P
L
A
N
S
T
A
P
I
S
F
E
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
P19
L
I
F
L
L
L
S
P
P
T
H
A
N
R
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.8
87.7
79.5
N.A.
85.5
85.7
N.A.
63.2
84.2
42.5
74.7
N.A.
40.4
N.A.
44
N.A.
Protein Similarity:
100
79.4
89.9
84.6
N.A.
91.1
92.2
N.A.
77
90.3
63.5
85.2
N.A.
60.6
N.A.
61.5
N.A.
P-Site Identity:
100
26.6
53.3
33.3
N.A.
40
40
N.A.
13.3
20
13.3
26.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
46.6
66.6
46.6
N.A.
66.6
66.6
N.A.
53.3
26.6
20
40
N.A.
40
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
42
17
67
17
0
9
9
0
67
9
% A
% Cys:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
17
% D
% Glu:
0
0
0
0
0
0
0
0
17
0
0
0
9
9
50
% E
% Phe:
0
0
25
9
9
0
0
0
0
25
0
25
0
0
0
% F
% Gly:
25
9
0
0
0
25
0
0
50
0
9
0
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
34
9
0
0
9
9
0
0
9
0
0
42
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% K
% Leu:
25
9
17
50
9
9
9
0
0
25
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
9
9
0
0
0
0
0
9
0
9
0
9
% N
% Pro:
0
9
9
0
9
0
0
9
17
17
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
9
0
0
0
0
0
9
0
0
9
0
% R
% Ser:
0
0
17
9
17
9
17
17
0
0
50
59
0
0
0
% S
% Thr:
0
0
17
0
25
0
42
9
0
17
0
9
0
9
0
% T
% Val:
9
17
0
0
9
0
9
0
0
0
9
0
25
9
0
% V
% Trp:
17
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _