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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP2
All Species:
17.27
Human Site:
S186
Identified Species:
47.5
UniProt:
Q05923
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05923
NP_004409.1
314
34400
S186
Y
L
F
L
G
S
C
S
H
S
S
D
L
Q
G
Chimpanzee
Pan troglodytes
XP_520046
394
42978
Y209
F
L
Y
L
G
S
A
Y
H
A
A
R
R
D
M
Rhesus Macaque
Macaca mulatta
XP_001111118
201
21316
S80
A
L
P
P
P
A
G
S
K
T
S
C
S
D
P
Dog
Lupus familis
XP_854441
314
33913
S186
Y
L
F
L
G
S
C
S
H
S
S
D
L
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q05922
318
34528
N190
Y
L
Y
L
G
S
C
N
H
S
S
D
L
Q
G
Rat
Rattus norvegicus
Q64623
367
39523
Y187
F
L
Y
L
G
S
A
Y
H
A
S
R
K
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512829
379
42172
Y189
F
L
Y
L
G
S
A
Y
H
A
S
K
C
E
F
Chicken
Gallus gallus
Q9PW71
375
41034
Y190
F
L
Y
L
G
S
A
Y
H
A
A
R
R
D
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003451
333
36736
H192
F
L
F
L
G
S
A
H
H
S
S
R
R
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
61.1
87.5
N.A.
85.8
46.5
N.A.
41.4
44.2
N.A.
51
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
55
61.7
90.1
N.A.
88
59.4
N.A.
55.4
56.2
N.A.
65.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
20
100
N.A.
86.6
40
N.A.
40
33.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
33.3
100
N.A.
100
60
N.A.
66.6
60
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
12
56
0
0
45
23
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
34
0
0
0
0
12
12
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
34
0
45
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% E
% Phe:
56
0
34
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
89
0
12
0
0
0
0
0
0
0
34
% G
% His:
0
0
0
0
0
0
0
12
89
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
0
0
12
12
0
0
% K
% Leu:
0
100
0
89
0
0
0
0
0
0
0
0
34
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
12
12
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
45
34
0
0
% R
% Ser:
0
0
0
0
0
89
0
34
0
45
78
0
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
0
56
0
0
0
0
45
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _