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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FPGS All Species: 16.36
Human Site: S173 Identified Species: 30
UniProt: Q05932 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05932 NP_001018088.1 587 64609 S173 T K D G S C V S M P P Y F R F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094027 589 64667 S173 T K D G S C V S M P P Y F R F
Dog Lupus familis XP_851481 588 64991 V173 T K D S N S C V S M P A Y F R
Cat Felis silvestris
Mouse Mus musculus P48760 587 64889 S173 F K D D S H V S M P S Y F R F
Rat Rattus norvegicus NP_001139597 587 65251 S173 F K D D S H I S M P S Y F R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998602 572 63143 S175 T K D A H G G S M P A Y F R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397249 440 49749 G79 I H V A G T K G K G S T C A Y
Nematode Worm Caenorhab. elegans Q09509 510 56414 F148 E Q M F A E E F F H V Y D I I
Sea Urchin Strong. purpuratus XP_796835 647 71198 K176 T K E D Y D G K M P A Y F R F
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001152065 557 61781 P181 D K T G D G V P M P A Y F R F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196217 571 63327 M189 R T N E E I P M P T Y F R F L
Baker's Yeast Sacchar. cerevisiae Q08645 548 62133 S175 R I N G E P I S E E K F A K Y
Red Bread Mold Neurospora crassa O13492 528 58506 L167 F F E V W D R L E T S Q L A K
Conservation
Percent
Protein Identity: 100 N.A. 93.8 87 N.A. 81.4 80.9 N.A. N.A. N.A. N.A. 59.9 N.A. N.A. 32.8 35.9 41.1
Protein Similarity: 100 N.A. 95.9 91.6 N.A. 87.9 87.7 N.A. N.A. N.A. N.A. 72.4 N.A. N.A. 50.9 50.9 55.3
P-Site Identity: 100 N.A. 100 26.6 N.A. 73.3 66.6 N.A. N.A. N.A. N.A. 66.6 N.A. N.A. 0 6.6 53.3
P-Site Similarity: 100 N.A. 100 40 N.A. 73.3 73.3 N.A. N.A. N.A. N.A. 66.6 N.A. N.A. 6.6 20 60
Percent
Protein Identity: N.A. 35.6 N.A. 35.6 37.1 34.7
Protein Similarity: N.A. 49.2 N.A. 50.9 52.1 50.4
P-Site Identity: N.A. 60 N.A. 0 13.3 0
P-Site Similarity: N.A. 60 N.A. 13.3 46.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 8 0 0 0 0 0 24 8 8 16 0 % A
% Cys: 0 0 0 0 0 16 8 0 0 0 0 0 8 0 0 % C
% Asp: 8 0 47 24 8 16 0 0 0 0 0 0 8 0 0 % D
% Glu: 8 0 16 8 16 8 8 0 16 8 0 0 0 0 0 % E
% Phe: 24 8 0 8 0 0 0 8 8 0 0 16 54 16 54 % F
% Gly: 0 0 0 31 8 16 16 8 0 8 0 0 0 0 0 % G
% His: 0 8 0 0 8 16 0 0 0 8 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 8 16 0 0 0 0 0 0 8 8 % I
% Lys: 0 62 0 0 0 0 8 8 8 0 8 0 0 8 8 % K
% Leu: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 8 % L
% Met: 0 0 8 0 0 0 0 8 54 8 0 0 0 0 0 % M
% Asn: 0 0 16 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 8 8 8 54 24 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 16 0 0 0 0 0 8 0 0 0 0 0 8 54 8 % R
% Ser: 0 0 0 8 31 8 0 47 8 0 31 0 0 0 0 % S
% Thr: 39 8 8 0 0 8 0 0 0 16 0 8 0 0 0 % T
% Val: 0 0 8 8 0 0 31 8 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 8 62 8 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _