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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FPGS All Species: 19.09
Human Site: S33 Identified Species: 35
UniProt: Q05932 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05932 NP_001018088.1 587 64609 S33 V A A R R G L S A W P V P Q E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094027 589 64667 S33 V A A Q R G L S A W P V P Q E
Dog Lupus familis XP_851481 588 64991 S33 V K A R R G L S A W P A P Q E
Cat Felis silvestris
Mouse Mus musculus P48760 587 64889 S33 G P A R R G M S A G P A P Q E
Rat Rattus norvegicus NP_001139597 587 65251 S33 G A A Y R W L S A W P A P Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998602 572 63143 S35 G L S V R L S S T K A A P R Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397249 440 49749
Nematode Worm Caenorhab. elegans Q09509 510 56414 L11 L P Q T N R I L L P T T S S T
Sea Urchin Strong. purpuratus XP_796835 647 71198 T35 A A N R A S S T G Q S V V G S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001152065 557 61781 S38 L P G S V H P S L L L P R A M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196217 571 63327 H38 L H H H Y Q H H Q P H L P S P
Baker's Yeast Sacchar. cerevisiae Q08645 548 62133 N38 H P E R W K T N A L L R F T F
Red Bread Mold Neurospora crassa O13492 528 58506 T31 T H H H L F F T K R T M A S S
Conservation
Percent
Protein Identity: 100 N.A. 93.8 87 N.A. 81.4 80.9 N.A. N.A. N.A. N.A. 59.9 N.A. N.A. 32.8 35.9 41.1
Protein Similarity: 100 N.A. 95.9 91.6 N.A. 87.9 87.7 N.A. N.A. N.A. N.A. 72.4 N.A. N.A. 50.9 50.9 55.3
P-Site Identity: 100 N.A. 93.3 86.6 N.A. 66.6 73.3 N.A. N.A. N.A. N.A. 20 N.A. N.A. 0 0 20
P-Site Similarity: 100 N.A. 100 86.6 N.A. 73.3 73.3 N.A. N.A. N.A. N.A. 33.3 N.A. N.A. 0 13.3 26.6
Percent
Protein Identity: N.A. 35.6 N.A. 35.6 37.1 34.7
Protein Similarity: N.A. 49.2 N.A. 50.9 52.1 50.4
P-Site Identity: N.A. 6.6 N.A. 6.6 13.3 0
P-Site Similarity: N.A. 13.3 N.A. 20 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 31 39 0 8 0 0 0 47 0 8 31 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 39 % E
% Phe: 0 0 0 0 0 8 8 0 0 0 0 0 8 0 8 % F
% Gly: 24 0 8 0 0 31 0 0 8 8 0 0 0 8 0 % G
% His: 8 16 16 16 0 8 8 8 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 8 0 0 8 8 0 0 0 0 0 % K
% Leu: 24 8 0 0 8 8 31 8 16 16 16 8 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 8 % M
% Asn: 0 0 8 0 8 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 31 0 0 0 0 8 0 0 16 39 8 54 0 8 % P
% Gln: 0 0 8 8 0 8 0 0 8 8 0 0 0 39 0 % Q
% Arg: 0 0 0 39 47 8 0 0 0 8 0 8 8 8 0 % R
% Ser: 0 0 8 8 0 8 16 54 0 0 8 0 8 24 16 % S
% Thr: 8 0 0 8 0 0 8 16 8 0 16 8 0 8 8 % T
% Val: 24 0 0 8 8 0 0 0 0 0 0 24 8 0 0 % V
% Trp: 0 0 0 0 8 8 0 0 0 31 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _